HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS

Panfei Xing; Kuo Gao; Beng Wang; Jian Gao; Hui Yan; Jia Wen; Weisi Li; Yongqian Xu; Hongjuan Li; Jianxin Chen; Wei Wang; Shiguo Sun

doi:10.1039/C6CC00880A

HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS†

Panfei Xing,‡^a Kuo Gao,^b Beng Wang,^a Jian Gao,^b Hui Yan,^a Jia Wen,^a Weisi Li,^a Yongqian Xu,^a Hongjuan Li,^a Jianxin Chen,*^b Wei Wang*^b and Shiguo Sun*^a

Author affiliations

* Corresponding authors

^a College of Science, Northwest A&F University, Yangling, Shaanxi, China
E-mail: sunsg@nwsuaf.edu.cn

^b Beijing University of Chinese Medicine, Beijing, China
E-mail: cjx@bucm.edu.cn, wangwei@bucm.edu.cn

Abstract

HEPES is not suitable for fluorescence detection of HClO because it can be oxidized by HClO. A novel probe for HClO, which can selectively and sensitively detect HClO in absolute PBS, was developed on the basis of an oxidation reaction with an azo moiety. Furthermore, it works well in live mouse imaging.

Chemical Communications

HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS†

Abstract

Supplementary files

Article information

Download Citation

Author version available

Permissions

HEPES is not suitable for fluorescence detection of HClO: a novel probe for HClO in absolute PBS

Social activity

Search articles by author

Spotlight

Advertisements