Issue 23, 2016
From the journal:

Organic & Biomolecular Chemistry

An asymmetric approach to bicyclo[2.2.1]heptane-1-carboxylates via a formal [4 + 2] cycloaddition reaction enabled by organocatalysis†

Jian-Guo Fu,‡a   Yi-Fan Shan,‡a   Wang-Bin Sun,a   Guo-Qiang Lina  and  Bing-Feng Sun*a  

* Corresponding authors

a CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, 345 Lingling Road, Shanghai 200032, China
E-mail: bfsun@sioc.ac.cn

Abstract

An organocatalytic formal [4 + 2] cycloaddition reaction has been realized that permits rapid access to a wide range of bicyclo[2.2.1]heptane-1-carboxylates in a highly enantioselective manner from simple starting materials under mild and operationally simple conditions.

Graphical abstract: An asymmetric approach to bicyclo[2.2.1]heptane-1-carboxylates via a formal [4 + 2] cycloaddition reaction enabled by organocatalysis

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Article information

DOI
https://doi.org/10.1039/C6OB00814C
Article type
Communication
Submitted
16 Apr 2016
Accepted
18 May 2016
First published
19 May 2016
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2016,14, 5229-5232

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An asymmetric approach to bicyclo[2.2.1]heptane-1-carboxylates via a formal [4 + 2] cycloaddition reaction enabled by organocatalysis

J. Fu, Y. Shan, W. Sun, G. Lin and B. Sun, Org. Biomol. Chem., 2016, 14, 5229 DOI: 10.1039/C6OB00814C

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