Issue 49, 2018
From the journal:

Chemical Communications

Upconversion nanocrystal ‘armoured’ silica fibres with superior photoluminescence for miRNA detection†

Gang Wang,a   Yike Fu,a   Zhaohui Ren, ORCID logo a   Jie Huang,b   Serena Best,c   Xiang Li ORCID logo *a  and  Gaorong Hana  

* Corresponding authors

a State Key Laboratory of Silicon Materials, School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, People's Republic of China
E-mail: xiang.li@zju.edu.cn
Fax: +86-0571-88276240
Tel: +86-0571-88276240

b Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK

c Department of Materials Science and Metallurgy, University of Cambridge, Cambridge CB3 0FS, UK

Abstract

We have fabricated a flexible membrane, consisting of SiO2 nanofibres armoured with upconversion nanoparticles, exhibiting intense photoluminescence. These assemblies were subsequently grafted with molecular beacons to produce a biosensor suitable for the detection of specific microRNA and with applications in early cancer detection and point-of-care diagnosis.

Graphical abstract: Upconversion nanocrystal ‘armoured’ silica fibres with superior photoluminescence for miRNA detection

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Article information

DOI
https://doi.org/10.1039/C8CC03480J
Article type
Communication
Submitted
30 Apr 2018
Accepted
29 May 2018
First published
30 May 2018

Chem. Commun., 2018,54, 6324-6327

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Upconversion nanocrystal ‘armoured’ silica fibres with superior photoluminescence for miRNA detection

G. Wang, Y. Fu, Z. Ren, J. Huang, S. Best, X. Li and G. Han, Chem. Commun., 2018, 54, 6324 DOI: 10.1039/C8CC03480J

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