Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)

Fay Nicolson; Lauren E. Jamieson; Samuel Mabbott; Konstantinos Plakas; Neil C. Shand; Michael R. Detty; Duncan Graham; Karen Faulds

doi:10.1039/C8CC04267E

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Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)†

Fay Nicolson,

^a Lauren E. Jamieson,

^a Samuel Mabbott,

^a Konstantinos Plakas,

^b Neil C. Shand,

^c Michael R. Detty,

^b Duncan Graham

^a and Karen Faulds

*^a

Author affiliations

* Corresponding authors

^a Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow G1 1RD, UK
E-mail: karen.faulds@strath.ac.uk

^b Department of Chemistry, University at Buffalo, The State University of New York, New York 14260, USA

^c DSTL, Porton Down, Salisbury, SP4 0JQ, UK

Abstract

Through utilizing the depth penetration capabilities of SESORS, multiplexed imaging and classification of three singleplex nanotags and a triplex of nanotags within breast cancer tumour models is reported for the first time through depths of 10 mm using a handheld SORS instrument.

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Article information

DOI: https://doi.org/10.1039/C8CC04267E
Article type: Communication
Submitted: 29 May 2018
Accepted: 29 Jun 2018
First published: 16 Jul 2018
This article is Open Access

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Chem. Commun., 2018,54, 8530-8533

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Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)

F. Nicolson, L. E. Jamieson, S. Mabbott, K. Plakas, N. C. Shand, M. R. Detty, D. Graham and K. Faulds, Chem. Commun., 2018, 54, 8530 DOI: 10.1039/C8CC04267E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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Chemical Communications

Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)†

Abstract

Supplementary files

Article information

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Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS)

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