Issue 45, 2020
From the journal:

Chemical Communications

Modulation of emission and singlet oxygen photosensitisation in live cells utilising bioorthogonal phosphorogenic probes and protein tag technology†

Peter Kam-Keung Leung ORCID logo a  and  Kenneth Kam-Wing Lo ORCID logo *abc  

* Corresponding authors

a Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China
E-mail: bhkenlo@cityu.edu.hk

b State Key Laboratory of Terahertz and Millimeter Waves, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China

c Centre of Functional Photonics, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China

Abstract

Herein we report a strategy to utilise the bioorthogonal reactivity and phosphorogenic property of iridium(III) polypyridine nitrone complexes and SNAP-tag protein for the modulation of emission and singlet oxygen (1O2) photosensitisation in live cells.

Graphical abstract: Modulation of emission and singlet oxygen photosensitisation in live cells utilising bioorthogonal phosphorogenic probes and protein tag technology

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Article information

DOI
https://doi.org/10.1039/D0CC02056G
Article type
Communication
Submitted
19 Mar 2020
Accepted
20 Apr 2020
First published
21 Apr 2020

Chem. Commun., 2020,56, 6074-6077

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Modulation of emission and singlet oxygen photosensitisation in live cells utilising bioorthogonal phosphorogenic probes and protein tag technology

P. K. Leung and K. K. Lo, Chem. Commun., 2020, 56, 6074 DOI: 10.1039/D0CC02056G

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