Issue 39, 2020
From the journal:

Chemical Science

Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones†

Jinzhong Yao,ab   Zhangpei Chen,a   Lin Yu,a   Leiyang Lv, ORCID logo a   Dawei Caoa  and  Chao-Jun Li ORCID logo *a  

* Corresponding authors

a Department of Chemistry, FQRNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke St. W., Montreal, Quebec H3A 0B8, Canada
E-mail: cj.li@mcgill.ca

b College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, People's Republic of China

Abstract

A palladium-catalyzed hydroalkylation reaction of methylenecyclopropanes via highly selective C–C σ-bond scission was achieved under mild conditions, in which simple hydrazones served as carbanion equivalents. This method featured good functional group compatibility, affording high yields of C-alkylated terminal alkenes.

Graphical abstract: Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones

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Article information

DOI
https://doi.org/10.1039/D0SC01221A
Article type
Edge Article
Submitted
28 Feb 2020
Accepted
14 May 2020
First published
15 May 2020
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2020,11, 10759-10763

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Palladium-catalyzed hydroalkylation of methylenecyclopropanes with simple hydrazones

J. Yao, Z. Chen, L. Yu, L. Lv, D. Cao and C. Li, Chem. Sci., 2020, 11, 10759 DOI: 10.1039/D0SC01221A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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