Issue 5, 2008
From the journal:

CrystEngComm

Simple and quantitative mechanochemical preparation of the first zinc and copper complexes of the neuroleptic drug gabapentin†

Dario Braga,*a   Fabrizia Grepioni,a   Lucia Maini,a   Roberto Brescellob  and  Livius Cotarcab  

* Corresponding authors

a Department of Chemistry G. Ciamician, Via F. Selmi 2, Bologna, Italy
E-mail: dario.braga@unibo.it
Fax: +39 (0)51 2099456

b ZaCh System SpA, Via Dovaro 2, Lonigo (VI), Italy

Abstract

In this communication we describe the solid-state preparation and structural characterization of the first two coordination complexes of the neuroleptic drug gabapentin, obtained by grinding together solid gabapentin and the inorganic salts ZnCl2 and CuCl2·2H2O.

Graphical abstract: Simple and quantitative mechanochemical preparation of the first zinc and copper complexes of the neuroleptic drug gabapentin

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Article information

DOI
https://doi.org/10.1039/B719451J
Article type
Communication
Submitted
04 Nov 2007
Accepted
02 Jan 2008
First published
15 Jan 2008

CrystEngComm, 2008,10, 469-471

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Simple and quantitative mechanochemical preparation of the first zinc and copper complexes of the neuroleptic drug gabapentin

D. Braga, F. Grepioni, L. Maini, R. Brescello and L. Cotarca, CrystEngComm, 2008, 10, 469 DOI: 10.1039/B719451J

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