Themed collection Analyst Review Articles 2024

This review discusses the formation and manipulation of magnetic droplets on microfluidic chips and classifies related detection techniques. Applications in biomedicine were reviewed. Future development of this emerging field is provided.

Electrochemical detection of liver biomarkers, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin, gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), and albumin, all with vital physiological functions.

The review provides a detailed introduction to the sensing mechanisms of ion current rectification sensing technology based on glass nano/micron pipette, as well as their applications, existing problems, and challenges in cells/in vivo analysis.

Raman microscopy can reveal metabolic signatures and heterogeneity at the single cell level.

A myrid of aptamers were isolated thus far against SARS-CoV-2 by using in silico selection.

Biomedical silk protein optics has become the subject of intensive research aimed at solving the challenges associated with traditional medical devices in terms of biocompatibility and performance balance.

This minireview summarizes the recent advancements in impact electrochemistry-based biosensing over the past two to three years and provides insights into the future directions of this field.

The researchers detect viruses through various analyses based on three targets: nucleic acids, antigens, and antibodies.

We review emerging methods for the detection of acute respiratory tract infections using microfluidic technologies.

Specific antibodies against small molecules typically require modification into haptens and coupling with carriers to synthesize artificial antigens. Image created with BioRender.com.

This review classifies MEMS sensors (both physical and chemical) in terms of their targets and explains their fundamental principles and trends. It also introduces the parallelization of different types of sensors or sensing functions.

A tutorial review on scanning electrochemical cell microscopy (SECCM), offering practical guidances on instrumentation, probe fabrication, substrate preparation, and troubleshooting, to equip researchers in the field.

The research progress of MOF-based nanozymes with oxidoreductase-like activity.

The structure of phenoxy-1,2-dioxetane scaffolds is optimised to improve their photophysical properties, selectivity for disease-specific enzymes and bioimaging applications.

Molecularly imprinted polymer sensors, combined with electrochemical, optical, thermal, and acoustic detection technologies, detect biomarkers for key cardiovascular diseases: coronary artery disease, acute myocardial infarction, and heart failure.

The recent advances of MOF-based SERS substrates in quantitative analysis of food contaminants are reviewed including properties, main roles, categories, structures, preparation methods, and food-safety applications.

Optical detection technology can indirectly detect blood glucose levels non-invasively and the effective combination of body fluid collection and detection methods opens new possibilities for blood glucose scientific management.

The review highlights advancements in sensitivity-enhanced colorimetric and fluorescent LFTs for kidney biomarker detection, offering an overview of classical diagnostic methods, commercially available LFTs, dipsticks, and POCT for kidney diseases.

Mass spectrometry imaging (MSI) provides spatially-resolved molecular information across various samples, including plants, microbes, and food, thereby enhancing our understanding of agricultural systems.

Neurobiological research relies heavily on imaging techniques, such as fluorescence microscopy, to understand neurological function and disease processes.

Schematic illustration of EXPAR-based biosensing techniques.

The multi-module biosensing applications based on metal nanoparticles in terms of sensing principle, sensitivity, and accuracy are summarized and visualized.

A comprehensive review on the properties and versatile applications of fluorescent carbon dots in detecting nucleic acids, imaging nucleoli, and delivering genes.

This review summarizes progress made over the past five years in the development of solid-contact ion-selective electrodes (SC-ISEs) based on nanomaterials, and provides insights into the prospects for this field.

Patients with end-stage kidney disease (ESKD) rely on dialysis to remove toxins and stay alive.

Overview of recent studies on SERS for biomolecular complexities analysis.

We discuss recent analytic methods for assessing the function of bacterial transglycosylase (TGase), the first enzyme in peptidoglycan elongation, from the 1990s and present the discovery of TGase inhibitors as potential antibacterial agents.

Different purification techniques for carbon dots.

Rapid and sensitive detection of pathogens. CRISPR/Cas has strong potential and application prospects in the field of bacterial detection.

Overview of nanopores for single cell detection.

This review introduces the recent advances in dual-emission MOF-based ratiometric fluorescence sensors for various targets such as pH, temperature, ions, biomarkers, etc., over the last 5 years.

This review summarizes the recent advances in three-dimensional graphene structures, including preparation methods and their detection application in the biomedical field.