Themed collection UPCON24 – Upconversion Nanomaterials


Superfluorescent upconversion nanoparticles as an emerging second generation quantum technology material
Ultra-fast upconverted room temperature quantum superfluorescence promises more photons per unit time. This article explores superfluorescence and how these particles can be considered as second-generation quantum technology materials.
Nanoscale Horiz., 2025, Advance Article
https://doi.org/10.1039/D4NH00651H
Operando characterization of lithium battery internal temperatures via upconverting nanoparticle thermometry
Upconverting nanoparticle thermometry enables operando characterization of lithium battery internal temperatures with high temporal and spatial resolution.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01160D

Giving new life to an outdated spectrofluorometer for static and time-resolved UCNP optical characterization
Obsolescence of proprietary systems can render valuable scientific instruments useless. Here we refurbished and enhanced a spectrofluorometer, enabling full optical characterization of upconversion nanoparticles.
Nanoscale Adv., 2025, Advance Article
https://doi.org/10.1039/D5NA00330J

Bioconjugates of photon-upconversion nanoparticles with antibodies for the detection of prostate-specific antigen and p53 in heterogeneous and homogeneous immunoassays
Strategies for the surface modification of upconversion nanoparticles were explored, and the prepared conjugates were employed as labels in immunoassays for cancer biomarker detection.
Nanoscale, 2025,17, 11401-11412
https://doi.org/10.1039/D5NR00176E

The true atomistic structure of a disordered crystal: a computational study on the photon upconverting material β-NaYF4 and its Er3+-, Tm3+-, and Yb3+-doped derivates
True atomic positions were determined for β-NaYF4 (:Ln3+) using density functional theory. The arrangement of the F− ions closest to doping sites is strongly affected by the occupation of disordered sites reducing their effective point group to C1.
Nanoscale, 2025,17, 8599-8613
https://doi.org/10.1039/D4NR04880F

Surface-engineered core–shell upconversion nanoparticles for effective hypericin delivery and multimodal imaging
Poly(N,N-dimethylacrylamide-co-2-aminoethylacrylate)-alendronate-coated core–shell upconversion nanoparticles have considerable potential for effective delivery of hypericin to tumors. The particles enabled multimodal detection of cancer cells.
Nanoscale, 2025,17, 5838-5857
https://doi.org/10.1039/D4NR05348F

Small upconversion-ruthenium nanohybrids for cancer theranostics
NIR-triggered drug release from upconversion nanoparticles functionalized with mesoporous silica shells destroys the nuclei of cancer cells.
Nanoscale, 2025,17, 3809-3821
https://doi.org/10.1039/D4NR04210G

Intraperitoneal versus intravenous administration of Flamma®-conjugated PEG-alendronate-coated upconversion nanoparticles in a mouse pancreatic cancer model
New PEG-coated upconversion nanoparticles conjugated with Flamma® dye demonstrated superior imaging and targeting of pancreatic tumor-bearing mice after intraperitoneal administration.
Nanoscale Adv., 2025,7, 144-154
https://doi.org/10.1039/D4NA00764F
About this collection
Guest Edited by Niko Hildebrandt (McMaster University, Canada), Eva Hemmer (University of Ottawa, Canada), Fiorenzo Vetrone (INRS, Canada). This is a special collection based on UPCON 2024 which took place in Montréal, Canada. Published in Nanoscale Horizons, Nanoscale and Nanoscale Advances by the Royal Society of Chemistry, this collection covers many aspects connected to upconversion nanomaterials and their applications.