Themed collection Plant Natural Product Biosynthesis and Biotechnology

The post-ingestive modifications in herbivores are essential to the function of plant specialized metabolites. Here, we highlight recent advances and discuss the prospects of functional study to plant natural products.

Chemoenzymatic routes to plant natural products and analogues are described, highlighting the advantages of incorporating biocatalysis into synthetic strategies.

Yeast cell factories represent an alternative solution for the sustainable production of plant terpenoids.

Diterpenoid biosynthesis in plants is derived from photosynthetic pigment metabolism, and arose early in land plant evolution, enabling stockpiling of the extensive arsenal of (di)terpenoid natural products currently observed in this kingdom.

This review discusses genomics-, transcriptomics- and metabolomics-based plant biosynthetic pathway discovery, and highlights the potential for integrative omics approaches.

Plants shape their associated microbiota largely by synthesizing and exuding small molecules. This review highlights their roles, biosynthetic origins, and bioengineering potentials and strategies.

This review provides an up-to-date summary of mass spectrometry imaging, emphasizing different applications and recent innovations in natural product research.

This review provides a timely update on the needs for plant synthetic biology in expanding access to plant specialized metabolites. It discusses opportunities and technical challenges related to plant engineering and implementation.

This review focuses on biochemistry of recently identified transporters of plant specialized metabolites at the plasma membrane and tonoplast.

A significant subset of plant specialised metabolism genes are arranged in biosynthetic gene clusters. Here, we review these clusters and discuss their possible roles within the context of genome dynamics and metabolic evolution.

This review focuses on the biosynthesis and evolution of specialized metabolism in the Solanaceae (Nightshade) family.

This review summarizes the different hypotheses surrounding the biosynthesis of quinolizidine alkaloids in lupins and discusses strategies for gene discovery and pathway elucidation.