Themed collection Nanomaterials in drug delivery

Professor Hélder A. Santos and Dr Irina N. Savina introduce the RSC Advances themed collection on Nanomaterials in drug delivery.

In the past few decades, scientists have actively worked on developing effective drug delivery systems (DDSs) as means to control life-threatening diseases and challenging illnesses.

This review provides an update on the various mRNA preparations, carriers that can deliver these preparations and how they could potentially enhance the bone regeneration.

Zein a versatile biomaterial in the biomedical field. Easy to chemically functionalize with good emulsification properties, can be employed in drug delivery, fabrication of bioactive membranes and 3D scaffolds for tissue regeneration.

Biodegradable nanoparticles drastically alters lateral organization of lung surfactant lipid- peptide model system.

Block copolymer micelles with a functional core have been synthesized and evaluated for their drug delivery capability. High drug loading was observed due to strong ionic interactions, while cytotoxicity of polymers was found to be low.

We developed RGD peptide based ionizable lipids, which can be formulated into LNPs for integrin-dependent targeted mRNA delivery and gene editing applications.

A 3D printed reactor-in-a-centrifuge (RIAC) was developed to produce drug nanocrystals. Quercetin nanocrystals were manufactured at varying operational and formulation conditions, and had a small size (190–302 nm) and low size dispersity (PDI < 0.1).