Themed collection Remodelling of Biomembranes

19 items
Editorial

Introduction to remodeling of biomembranes

Reinhard Lipowsky and Rumiana Dimova introduce the Soft Matter themed issue on remodeling of biomembranes.

Graphical abstract: Introduction to remodeling of biomembranes
From the themed collection: Remodelling of Biomembranes
Perspective

Diffusive transport of nanoscale objects through cell membranes: a computational perspective

Clarifying the diffusion dynamics of nanoscale objects with cell membrane is critical for revealing fundamental physics in biological systems. This perspective highlights the advances in computational and theoretical aspects of this emerging field.

Graphical abstract: Diffusive transport of nanoscale objects through cell membranes: a computational perspective
From the themed collection: Remodelling of Biomembranes
Review Article

Comparing physical mechanisms for membrane curvature-driven sorting of BAR-domain proteins

We review current theoretical models for curvature sensing of BAR-domain proteins, test the models on 2 proteins, and present new electron microscopy data on the organization of BAR domains on tubes.

Graphical abstract: Comparing physical mechanisms for membrane curvature-driven sorting of BAR-domain proteins
From the themed collection: Remodelling of Biomembranes
Review Article

Long-range mechanical signaling in biological systems

Cells can respond to signals generated by other cells that are remarkably far away.

Graphical abstract: Long-range mechanical signaling in biological systems
From the themed collection: Remodelling of Biomembranes
Open Access Review Article

ENTH domain-dependent membrane remodelling

Cellular membranes are anything but flat structures.

Graphical abstract: ENTH domain-dependent membrane remodelling
From the themed collection: Remodelling of Biomembranes
Open Access Review Article

Increasing complexity in small-angle X-ray and neutron scattering experiments: from biological membrane mimics to live cells

We review compositional models for analyzing small-angle X-ray and neutron scattering data of complex membrane mimics and live cells.

Graphical abstract: Increasing complexity in small-angle X-ray and neutron scattering experiments: from biological membrane mimics to live cells
From the themed collection: Remodelling of Biomembranes
Open Access Paper

Active shape oscillations of giant vesicles with cyclic closure and opening of membrane necks

During each active oscillation cycle, the vesicle shape undergoes a symmetry-breaking transformation from an up-down symmetric to an up-down asymmetric dumbbell followed by the reverse symmetry-restoring transformation.

Graphical abstract: Active shape oscillations of giant vesicles with cyclic closure and opening of membrane necks
From the themed collection: Remodelling of Biomembranes
Paper

Unraveling topology-induced shape transformations in dendrimersomes

Using cell-mimetic dendrimersomes we demonstrated how changes in the molecular topology of the amphiphilic Janus dendrimers forming the bilayer lead to the evolution of shape without the need for any active cellular machinery.

Graphical abstract: Unraveling topology-induced shape transformations in dendrimersomes
From the themed collection: Remodelling of Biomembranes
Paper

Annexin A4 trimers are recruited by high membrane curvatures in giant plasma membrane vesicles

Protein structure and curvature sensing for annexin A4 trimers are coupled. These findings may provide new insight for the mechanisms underlying plasma membrane repair.

Graphical abstract: Annexin A4 trimers are recruited by high membrane curvatures in giant plasma membrane vesicles
From the themed collection: Remodelling of Biomembranes
Open Access Paper

Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages

Lipid membranes are ubiquitous biological organizers, required for structural and functional compartmentalization of the cell and sub-cellular organelles.

Graphical abstract: Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages
From the themed collection: Remodelling of Biomembranes
Open Access Paper

Reversible membrane deformations by straight DNA origami filaments

Reversible MgCl2-induced blunt-end polymerization of membrane-bound straight DNA origami monomers into filaments leads to protruding deformations on freestanding lipid membranes.

Graphical abstract: Reversible membrane deformations by straight DNA origami filaments
From the themed collection: Remodelling of Biomembranes
Open Access Paper

Membrane morphologies induced by mixtures of arc-shaped particles with opposite curvature

Three-way junctions of membrane tubules are stabilized by particles generating membrane curvature opposite to the particles that induce the tubules.

Graphical abstract: Membrane morphologies induced by mixtures of arc-shaped particles with opposite curvature
From the themed collection: Remodelling of Biomembranes
Open Access Paper

Particle engulfment by strongly asymmetric membranes with area reservoirs

We study the engulfment of solid particles by membranes with area reservoirs that are stabilized by large spontaneous curvature, and show that the properties of the reservoir can influence membrane remodelling processes.

Graphical abstract: Particle engulfment by strongly asymmetric membranes with area reservoirs
From the themed collection: Remodelling of Biomembranes
Paper

The transbilayer distribution of polyunsaturated phospholipids determines their facilitating effect on membrane deformation

In the cell, membrane deformation and fission (collectively referred to as ‘budding’) is driven by specific protein machineries but is also influenced by lipid composition.

Graphical abstract: The transbilayer distribution of polyunsaturated phospholipids determines their facilitating effect on membrane deformation
From the themed collection: Remodelling of Biomembranes
Open Access Paper

Simple sugars shape giant vesicles into multispheres with many membrane necks

A lipid vesicle exposed to an interior sucrose and an exterior glucose solution can attain a variety of multispherical shapes with different numbers of large and small spheres. For each shape, all spheres are connected by narrow membrane necks.

Graphical abstract: Simple sugars shape giant vesicles into multispheres with many membrane necks
From the themed collection: Remodelling of Biomembranes
Paper

Quantitative investigation of negative membrane curvature sensing and generation by I-BARs in filopodia of living cells

We analyze diffraction-limited filopodia of living cells to quantify negative curvature sensing and generation for two prototypic I-BAR domains.

Graphical abstract: Quantitative investigation of negative membrane curvature sensing and generation by I-BARs in filopodia of living cells
From the themed collection: Remodelling of Biomembranes
Paper

Actin shells control buckling and wrinkling of biomembranes

Compression of membrane–actin cell mimics generates buckling and wrinkling depending on actin thickness.

Graphical abstract: Actin shells control buckling and wrinkling of biomembranes
From the themed collection: Remodelling of Biomembranes
Paper

Structured and intrinsically disordered domains within Amphiphysin1 work together to sense and drive membrane curvature

Cellular membranes undergo remodeling during many cellular processes including endocytosis. Here we elucidated the functional role of the disordered domain in Amphiphysin1 by gradually truncating it, creating a family of mutant proteins.

Graphical abstract: Structured and intrinsically disordered domains within Amphiphysin1 work together to sense and drive membrane curvature
From the themed collection: Remodelling of Biomembranes
Open Access Correction

Correction: Long-range mechanical signaling in biological systems

From the themed collection: Remodelling of Biomembranes
19 items

About this collection

This themed collection, guest-edited by Professors Rumiana Dimova & Reinhard Lipowsky (Max Planck Institute (MPI) of Colloids and Interfaces) provides state-of-the-art reviews on membrane processes, as well as original articles at the forefront of research on remodelling biomembranes.

Biomembranes consist of fluid bilayers with many lipid and protein components. This fluidity allows the membranes to respond to different environmental cues by changing their local molecular composition, as well as their shape and topology.

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