Themed collection Organic Chemistry Frontiers 10th Anniversary Collection

The conventional and more recent metallaphotoredox-mediated reductive Co-catalysis for the coupling of olefins and alkynes is highlighted demonstrating the great potential of these approaches for the creation of advanced and complex synthons.

Chiral sp³-geminated bimetallic reagents based on B, Si, and Sn have drawn much attention due to their unique structure and reaction mode. This review summarizes the synthesis of nonracemic gem-borylstannyl, gem-borylsilyl, and gem-diboryl compounds.

This review offers a comprehensive overview of recent advancements in the asymmetric construction of C–N bonds involving radical intermediates.

Developments in the synthesis of indolizines during the last decade are reviewed, with special emphasis given to strategies relying on pyrrole derivatives and on π-expanded systems.

Artificial intelligence (AI) is transforming molecular catalysis by addressing long-standing challenges in retrosynthetic design, catalyst design, reaction development, and autonomous experimentation.

The recent advances on the application of electrocyclic reactions in the total synthesis of notable natural products are summarized.

This review covers synthetic approaches towards crystalline 2D conjugated polymers linked by imines, pyrazines, vinylenes, C–C, or imidazoles. It explores the interplay between structures and properties, highlighting their prospects in electronics.

This review outlines recent progress in the total synthesis of cyclopropane-containing natural products, with a particular focus on the application of novel synthetic methodologies and tactics for assembling naturally occurring three-membered rings.

Polycyclic aromatic dicarboximides (PADIs) as represented by naphthalene and perylene bis(dicarboximide) are useful molecules for a variety of functional materials and remain important synthetic targets for organic chemists.

This review covers the development and recent progress in transition-metal-catalyzed C–Ge coupling reactions. The goal is to provide a clear overview of the field, identify current challenges, and inspire further applications in this growing area.

This review has summarized the development of organocatalytic asymmetric [3 + 3] cycloadditions and given insights into the remaining challenges to promote the future development of this field.

This review presents a comprehensive overview of the synthesis of cyclopropanes using enantioselective Michael Initiated Ring Closure (MIRC) reactions.

This review is focused on the chemistry of frustrated Lewis pairs (FLPs) with alkynes and surveys the range of stoichiometric and catalytic reactions enabled by this concept.

Iridium-catalyzed C–H activation and borylation has become as a powerful synthetic tool in the past few decades because of the widespread applicability and versatility of organoboron compounds.