Issue 6, 2013
From the journal:

Chemical Communications

Promoting strand exchange in a DNA-templated transfer reaction†

Julia Michaelis,a   Atsushi Maruyamab  and  Oliver Seitz*a  

* Corresponding authors

a Humboldt-Universität zu Berlin, Institut für Chemie, Brook-Taylor-Str. 2, 12489 Berlin, Germany
E-mail: oliver.seitz@chemie.hu-berlin.de
Fax: +49 30 2093 7266
Tel: +49 30 2093 7446

b Institute for Materials Chemistry and Engineering, Kyushu University, Motooka 744, Fukuoka 819-0395, Nishi-ku, Japan
E-mail: maruyama@ms.ifoc.kyushu-u.ac.jp
Tel: +81 92 802 2521

Abstract

Most DNA-templated reactions suffer from product inhibition. We explored a DNA-triggered fluorophor transfer reaction and demonstrated that comb-type polylysine–polydextran copolymers increase the turnover in template by promoting strand exchange.

Graphical abstract: Promoting strand exchange in a DNA-templated transfer reaction

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Article information

DOI
https://doi.org/10.1039/C2CC36162K
Article type
Communication
Submitted
24 Aug. 2012
Accepted
23 Nov. 2012
First published
26 Nov. 2012

Chem. Commun., 2013,49, 618-620

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Promoting strand exchange in a DNA-templated transfer reaction

J. Michaelis, A. Maruyama and O. Seitz, Chem. Commun., 2013, 49, 618 DOI: 10.1039/C2CC36162K

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