Issue 47, 2009
From the journal:

Chemical Communications

Preparation of highly substituted tetrahydropyrans via a metal assisted dipolar cycloaddition reaction†

Eric A. Allart,a   Steven D. R. Christie,*a   Gareth J. Pritchard*a  and  Mark R. J. Elsegooda  

* Corresponding authors

a Department of Chemistry, Loughborough University, Loughborough, Leicestershire, UK
E-mail: s.d.christie@lboro.ac.uk, g.j.pritchard@lboro.ac.uk
Fax: +44 (0)1509 223925
Tel: +44 (0)1509 222586

Abstract

A range of highly substituted tetrahydropyrans have been prepared by reaction of a donor–acceptor cyclobutane, where the donor is a metal–alkyne complex, with an aldehyde under Lewis acid conditions.

Graphical abstract: Preparation of highly substituted tetrahydropyrans via a metal assisted dipolar cycloaddition reaction

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Article information

DOI
https://doi.org/10.1039/B917332C
Article type
Communication
Submitted
24 Aug 2009
Accepted
06 Oct 2009
First published
22 Oct 2009

Chem. Commun., 2009, 7339-7341

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Preparation of highly substituted tetrahydropyrans via a metal assisted dipolar cycloaddition reaction

E. A. Allart, S. D. R. Christie, G. J. Pritchard and M. R. J. Elsegood, Chem. Commun., 2009, 7339 DOI: 10.1039/B917332C

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