Copper-catalyzed direct decarboxylative hydrosulfonylation of aryl propiolic acids with sulfonylhydrazides leading to vinylsulfones

Abstract

A simple and facile protocol for copper-catalyzed direct decarboxylative hydrosulfonylation of aryl propiolic acids with sulfonylhydrazides was developed, establishing an attractive approach to obtain (E)-vinylsulfones under base-free conditions. Remarkable features of this reaction include using a simple copper catalyst in air and good tolerance to aromatic and aliphatic sulfonylhydrazides.