Issue 8, 2017

Sulfur dioxide prodrugs: triggered release of SO2via a click reaction

Abstract

Sulfur dioxide (SO2) is being recognized as a possible endogenous gasotransmitter with importance on par with that of NO, CO, and H2S. Herein we describe a series of SO2 prodrugs that are activated for SO2 release via a bioorthogonal click reaction. The release rate can be tuned by adjusting the substituents on the prodrug.

Graphical abstract: Sulfur dioxide prodrugs: triggered release of SO2via a click reaction

Supplementary files

Article information

Article type
Communication
Submitted
04 Nov 2016
Accepted
20 Dec 2016
First published
21 Dec 2016

Chem. Commun., 2017,53, 1370-1373

Sulfur dioxide prodrugs: triggered release of SO2via a click reaction

W. Wang, X. Ji, Z. Du and B. Wang, Chem. Commun., 2017, 53, 1370 DOI: 10.1039/C6CC08844A

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