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Retraction: The extract from the roots of Rose odorata sweet var. gigantean (Coll. et Hemsl.) Rehd. et Wils attenuates DSS-induced ulcerative colitis by regulating the Nrf2/NF-κB signaling pathways

Xinyu Liab, Rui Liua, Yanmin Zhaoab, Naying Gaobc, Xin Jinb, Xiaoxia Gaoc, Tan Li*b and Dailin Liu*ab
aTianjin University of Traditional Chinese Medicine, Tianjin 300193, China
bTianjin Key Laboratory for Prevention and Control of Occupational and Environmental Hazard, Logistics University of Chinese People’s Armed Police Force, Tianjin 300309, P. R. China. E-mail: dailinlch@163.com; Tanli20042001@163.com; Fax: +86-22-84876608; Fax: +86-22-84876589; Tel: +86-22-84876608 Tel: +86-22-84876589
cDepartment of Traditional Chinese Medicine, Guangdong Pharmaceutical College, Guangdong 510006, P. R. China

Received 1st October 2024 , Accepted 1st October 2024

First published on 7th October 2024


Abstract

Retraction of ‘The extract from the roots of Rose odorata sweet var. gigantean (Coll. et Hemsl.) Rehd. et Wils attenuates DSS-induced ulcerative colitis by regulating the Nrf2/NF-κB signaling pathways’ by Xinyu Li et al., RSC Adv., 2020, 10, 9450–9461, https://doi.org/10.1039/C9RA10747A.


The Royal Society of Chemistry hereby wholly retracts this RSC Advances article due to concerns with the image within Fig. 5A, the reliability of the western blot data, and unattributed text overlap with ref. 1.

In Fig. 5A, the ROE (250 mg kg−1) column on the top (NrF2) line and bottom (NF-KB) line appear to have similarities consistent with the image being flipped and rotated.

The raw data for the western blot panels in Fig. 7 have no visible background and appear over-contrasted. The individual bands are uncharacteristically very uniform and regular in shape, indicating that they may not be genuine.

Given the significance of the concerns about the validity of both the data in the article and the raw data provided by the authors, the findings presented in this paper are not reliable.

The authors were informed about the retraction of this article but have not responded.

Laura Fisher, Executive Editor, RSC Advances

22nd August 2024

References

  1. D. Liu, X. Huo, L. Gao, J. Zhang, H. Ni and L. Cao, NF-κB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice, Biomed. Pharmacother., 2018, 102, 922–929,  DOI:10.1016/j.biopha.2018.03.130.

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