A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions†
Abstract
A very short and efficient synthesis of the important
* Corresponding authors
a
Department of Chemistry & Pharmaceutical Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, the Netherlands
E-mail:
e.ruijter@few.vu.nl
Fax: +31 20 59 87488
Tel: +31 20 59 87462
b School of Chemistry, University of Manchester, Manchester Inter-disciplinary Biocentre, 131 Princess Street, Manchester, UK
A very short and efficient synthesis of the important
A. Znabet, M. M. Polak, E. Janssen, F. J. J. de Kanter, N. J. Turner, R. V. A. Orru and E. Ruijter, Chem. Commun., 2010, 46, 7918 DOI: 10.1039/C0CC02823A
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