Issue 40, 2010
From the journal:

Chemical Communications

Site-specific photochemical RNA editing†

Kenzo Fujimoto,*a   Kaoru Konishi-Hiratsuka,a   Takashi Sakamotoa  and  Yoshinaga Yoshimuraa  

* Corresponding authors

a School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahi-dai, Nomi, Ishikawa, Japan
E-mail: kenzo@jaist.ac.jp
Fax: (+81) 761-51-1671
Tel: (+81) 761-51-1671

Abstract

Photo-induced artificial RNA editing was demonstrated using photo-reactive oligonucleotides containing 3-cyanovinylcarbazole nucleoside. This non-enzymatic and sequence-specific methodology will make a major contribution to the elucidation of RNA functions including non-coding RNAs and to the development of drugs based on sequence-specific RNA editing.

Graphical abstract: Site-specific photochemical RNA editing

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Article information

DOI
https://doi.org/10.1039/C0CC03151H
Article type
Communication
Submitted
10 Aug 2010
Accepted
01 Sep 2010
First published
17 Sep 2010

Chem. Commun., 2010,46, 7545-7547

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Site-specific photochemical RNA editing

K. Fujimoto, K. Konishi-Hiratsuka, T. Sakamoto and Y. Yoshimura, Chem. Commun., 2010, 46, 7545 DOI: 10.1039/C0CC03151H

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