Issue 10, 2014
From the journal:

RSC Advances

Tailored dual coating of magnetic nanoparticles for enhanced drug loading†

Lichao Song,a   Mingjing Sun,b   Yanjun Zhao*c  and  Zheng Wang*c  

* Corresponding authors

a Department of Pharmacy, National Clinical Research Center of Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Huanhuxi Road, Hexi District, Tianjin 300060, China

b College of Science, Tianjin University of Science & Technology, 29 TEDA 13th Avenue, Tianjin 300457, China

c Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, School of Pharmaceutical Science & Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China
E-mail: zhaoyj@tju.edu.cn, wangzheng2006@tju.edu.cn
Fax: +86-22-27404018
Tel: +86-22-27404018

Abstract

A novel type of superparamagnetic iron oxide nanoparticles (SPIONs) with dual coatings was reported to address the problem of poor loading capability of traditional SPIONs. It was found that the loading of a model drug, paclitaxel, in such SPIONs increased up to ca. 190 times.

Graphical abstract: Tailored dual coating of magnetic nanoparticles for enhanced drug loading

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Article information

DOI
https://doi.org/10.1039/C3RA42861C
Article type
Communication
Submitted
08 Jun 2013
Accepted
10 Dec 2013
First published
10 Dec 2013

RSC Adv., 2014,4, 4893-4896

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Tailored dual coating of magnetic nanoparticles for enhanced drug loading

L. Song, M. Sun, Y. Zhao and Z. Wang, RSC Adv., 2014, 4, 4893 DOI: 10.1039/C3RA42861C

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