Themed collection Nanoscale 2025 Emerging Investigators
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External strategies for enhanced sensing performance of self-powered polyvinylidene fluoride-based sensors
External strategies such as electrode design, stress/heat transfer improvements, microstructure optimization, and multifunctional synergy show great potential for improving sensing performance of PVDF-based sensors. Images reproduced with permission, full details in paper.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05200E
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Sustainable nanofibrous membranes for air filtration, water purification and oil removal
The increasing demand for sustainable solutions to address environmental and energy challenges has driven the development of advanced materials. This paper highlights recent advancements in the development of sustainable nanofibrous membranes.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04673K
Leveraging the dual role of ROS in liver diseases with nanomaterials: clearing and amplifying for therapy
The dual role of ROS in liver diseases, and the potential of nanomaterials with catalytic activity for therapeutic applications are examined.
Nanoscale, 2025,17, 3688-3697
https://doi.org/10.1039/D4NR04469J
NIR-II upconversion nanomaterials for biomedical applications
This review provides a comprehensive overview of recent biomedical applications of upconversion nanomaterials specifically within the near-infrared two-region (NIR-II) window (1000–1700 nm).
Nanoscale, 2025,17, 2985-3002
https://doi.org/10.1039/D4NR04445B
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Advances in integrated power supplies for self-powered bioelectronic devices
The emerging integrated power supplies for self-powered bioelectronic devices over the past few years are summarized. Additionally, the challenges and future perspectives in self-powered device design and manufacturing are also indicated.
Nanoscale, 2025,17, 2423-2437
https://doi.org/10.1039/D4NR04645E
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Design strategies and performance enhancements of PVDF-based flexible electrolytes for high-performance all-solid-state lithium metal batteries
Lithium metal is considered one of the most promising anode materials for lithium batteries due to its high theoretical specific capacity (3860 mA h g−1) and low redox potential (−3.04 V).
Nanoscale, 2025,17, 2408-2422
https://doi.org/10.1039/D4NR04583A
Organic semiconductor bulk heterojunctions for solar-to-chemical conversion: recent advances and challenges
This minireview highlights recent progress in BHJ-based photoelectrochemical cells and photocatalysts for solar-to-chemical conversions.
Nanoscale, 2025,17, 1889-1921
https://doi.org/10.1039/D4NR03938F
Advanced applications in enzyme-induced electrospun nanofibers
Guidelines for tailored enzyme-induced electrospun nanofiber immobilization techniques: aligning fabrication methods with future application requirements.
Nanoscale, 2024,16, 19606-19619
https://doi.org/10.1039/D4NR03404J
Nanoscale high-entropy alloys for solar and thermal applications
This review highlights the advantages of non-annealing synthesis, emphasizing the importance of in situ characterization, multi-level simulations and machine learning to accelerate photo-/thermocatalytic research in nanoscale high-entropy alloys.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04697H
Modulation anisotropy of nanomaterials toward monolithic integrated polarization-sensitive photodetectors
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05034G
Recent advances in poly(amino acids), polypeptides, and their derivatives in drug delivery
This review systematically describes the preparation of poly(amino acids) and peptides, and their use in drug loading for various diseases, offering insights for research and clinical applications of degradable biomedical polymers.
Nanoscale, 2025,17, 3549-3584
https://doi.org/10.1039/D4NR04481A
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Flexible, Wearable Mechano-Acoustic Sensors for Body Sound Monitoring Applications
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05145A
Strategic design of emerging (K,Na)NbO3-based perovskites for high-performance piezocatalysis and photo-piezocatalysis
This comprehensive review of (K,Na)NbO3-based perovskites explores design strategies, mechanisms, and applications in piezocatalysis and photo-piezocatalysis for sustainable environmental and energy solutions.
Nanoscale, 2025,17, 2931-2960
https://doi.org/10.1039/D4NR04415K
Patterning technologies of quantum dots for color-conversion micro-LED display applications
A comprehensive summary of patterning technologies of quantum dots for construction of color-conversion layers in full-color micro-LED displays is provided.
Nanoscale, 2025,17, 1764-1789
https://doi.org/10.1039/D4NR03925D
Single atoms meeting 2D materials: an excellent configuration for photocatalysis
The state-of-art progress in single-atom tuned two-dimensional materials is reviewed to clarify the distinctive advantages in photocatalysis and present the crucial structure–activity relationship for improved performance.
Nanoscale, 2024,16, 22077-22098
https://doi.org/10.1039/D4NR03787A
Recent advances in flexible multifunctional electrochromic devices
This review comprehensively summarizes the recent development of flexible multifunctional electrochromic devices, including energy harvesting, energy storage, multicolor displays, and smart windows.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04074K
Rational nanoparticle design for efficient biomolecule delivery in plant genetic engineering
Nanoparticle-mediated approaches to plant genetic engineering represent key advances in agriculture, offering benefits beyond conventional techniques. This review discusses essential nanoparticle design considerations to optimize delivery efficiency.
Nanoscale, 2024,16, 21264-21278
https://doi.org/10.1039/D4NR03760J
Recent advances in tungsten oxide-based chromogenic materials: photochromism, electrochromism, and gasochromism
Applications of WOx in photochromic, electrochromic, and gasochromic materials and devices.
Nanoscale, 2024,16, 21279-21293
https://doi.org/10.1039/D4NR03781B
New paradigms of 2D layered material self-driven photodetectors
The burgeoning initiatives implementing self-driven 2D layered material photodetectors have been presented, heralding new avenues for the next-generation integrated and miniaturized optoelectronic industry.
Nanoscale, 2024,16, 20811-20841
https://doi.org/10.1039/D4NR03543G
Developments, challenges and future trends in advanced sustainable machining technologies for preparing array micro-holes
The use of array micro-holes is becoming increasingly prevalent across a range of industries, including the aerospace, automotive, electronics, medical and chemical industries.
Nanoscale, 2024,16, 19938-19969
https://doi.org/10.1039/D4NR02910K
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SnSb as a long cycle life anode material for sodium-ion batteries enabled by a high concentration electrolyte
The performance of a SnSb Na-ion battery anode composed of nanolayers of Sn and Sb is reported, wherein the cycle life was significantly enhanced by the use of a high concentration electrolyte.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR03820G
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Slippery liquid-like surfaces as a promising solution for sustainable drag reduction
Fluid slip and drag reduction induced by durable slippery liquid-like surfaces (SLLSs) made from flexible polymers.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04507F
Nanoparticle-assembled interconnected PbO1.44 hollow spheres enabled by PVP-driven transformation of β-PbO2 and self-sacrificial templating for superior lithium storage
Nanoparticle-assembled interconnected PbO1.44 hollow spheres (NAHSs) were crafted by a robust strategy of PVP-driven transformation of β-PbO2 microspheres (MSs) combined with a self-sacrificial templating mechanism for superior lithium storage.
Nanoscale, 2025,17, 3023-3034
https://doi.org/10.1039/D4NR04763J
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Exfoliation of triazole-based C3N4.8, C3N6, and C3N7 nanosheets for efficient photocatalytic ammonia production
Triazole-based C3N7 nanosheets exhibit excellent photocatalytic ammonia production performance, attributed to their inherent properties of an optimised conduction band position and efficient charge separation.
Nanoscale, 2025,17, 2438-2443
https://doi.org/10.1039/D4NR03639E
Nucleic acid detection with single-base specificity integrating isothermal amplification and light-up aptamer probes
CLASSIC is a label-free DNA detection platform with single-nucleotide specificity and attomolar sensitivity. This assay offers rapid and sequence-specific DNA analysis through single-strand conversion and split light-up aptamer probes.
Nanoscale, 2024,16, 20067-20072
https://doi.org/10.1039/D4NR01638F
Protecting Li-metal anode with LiF-enriched solid electrolyte interphase derived from a fluorinated graphene additive
An LiF-enriched (composition-wise) and organic/inorganic uniform-distributed (structure-wise) SEI film architecture was derived by fluorinated graphene (F-Gr) sacrificial additive to promote efficient Li-metal protection.
Nanoscale, 2024,16, 19633-19641
https://doi.org/10.1039/D4NR02877E
Simultaneous formation of helical and sheet-like assemblies from short azapeptides enables spontaneous resolution
Bioinspired 1D helical and 2D sheet-like assemblies are combined to form a 3D homochiral assembly that allows spontaneous resolution.
Nanoscale, 2024,16, 19221-19227
https://doi.org/10.1039/D4NR02872D
Rational synthesis of carbon-rich hollow carbon nitride spheres for photocatalytic H2O2 production and Cr (VI) reduction
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05501B
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Spectral and dynamical properties of multiexcitons in semiconductor nanorods
Applying an MCMC sampling approach for global target analysis enables us to determine the contributions of multiple exciton decay via Auger recombination and the contribution of surface exciton states to the observed decay dynamics.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04692G
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Supramolecular electrostatic functionalization of 1T-MoS2 based on alkylammonium salts
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05515B
Multilevel, solar-blind, and thermostable physical unclonable functions based on host-sensitized luminescence of β-Ga2O3:Dy3+
The luminescent properties of β-Ga2O3:Dy3+ enable the development of optical PUF tags with exceptional encoding capacity, solar-blind response, and thermal stability, making them highly effective for anti-counterfeiting and encryption applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05237D
Kinetic analysis of silver nanowire synthesis: polyol batch and continuous millifluidic methods
Nucleation (k1) and growth (k2) rate constants for the polyol silver nanowire synthesis were determined for batch and millifluidic flow reactors (MFRs). The MFR rate constants are larger in magnitude and synthesize AgNWs faster than batch reactors.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR03812F
Controllable magnetism and an anomalous Hall effect in (Bi1−xSbx)2Te3-intercalated MnBi2Te4 multilayers
In (Bi1−xSbx)2Te3 intercalated MnBi2Te4 multilayers, structural engineering is employed to modulate both the anomalous Hall response and magnetism.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05486E
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Harnessing DFT and Machine Learning for Accurate Optical Gap Prediction in Conjugated Polymers
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR03702B
Nanoparticles Alter Locust Development and Behaviour
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR04993D
Morphology-tuned MnOx/TiO2 nanocatalysts for recycling PET plastic waste using biomass-derived ethylene glycol
This work elucidated the effect of TiO2 morphology on the structure–activity properties of MnOx/TiO2 nanocatalysts toward developing practically feasible catalytic routes for the plastic recycling industry.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05373G
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Studying The Effect of Dimensions and Spacer Ligands on The Optical Properties of 2D Metal Halide Perovskites
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05516K
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Inclusion of gold ions in tiara-like nickel hexanuclear nanoclusters
The inclusion properties of various metal ions in Ni6(PET)12 were investigated and it was found that it selectively includes gold ions.
Nanoscale, 2025,17, 3721-3727
https://doi.org/10.1039/D4NR04579C
Small-angle neutron scattering differentiates molecular-level structural models of nanoparticle interfaces
Small-angle neutron scattering can be utilized to distinguish structural models of nanoparticles with molecular- and Å-scale differences.
Nanoscale, 2025,17, 3798-3808
https://doi.org/10.1039/D4NR04365K
Stacked meshes with super-wettability via atmospheric plasma for efficient emulsion separation
An efficient emulsion separation strategy has been developed using multilayer stacked nylon meshes treated with atmospheric plasma with super-wettability.
Nanoscale, 2025,17, 3777-3786
https://doi.org/10.1039/D4NR04457F
A-site composition tuning in methylammonium-based metal halide perovskite colloidal nanocrystals
Methylammonium-based A-site composition tuning in lead halide perovskites via post-synthetic cross-ion exchange to generate phase-stable colloidal nanocrystals of FAxMA1−xPbI3 and CsxFAyMA1−x−yPbI3 (TCPbI3).
Nanoscale, 2025,17, 3787-3797
https://doi.org/10.1039/D4NR03422H
Ultra-confined plasmons reveal moiré patterns in twisted bilayer graphene–talc heterostructure
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR04532G
Self-Supporting Poly (3,4-ethylenedioxythiophene) and Fe3C Co-Decorated Electrospun Carbon Nanofibers as Li2S Supporter for Lithium Sulfur Batteries
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR04989F
Nano-spherical tip-based smoothing with minimal damage for 2D van der Waals heterostructures
Two-dimensional materials and their heterostructures have significant potential for future developments in materials science and optoelectronics due to their unique properties.
Nanoscale, 2025,17, 3095-3104
https://doi.org/10.1039/D4NR03583F
Construction of an Sc-NiFe-LDH electrocatalyst for highly efficient electrooxidation of 5-hydroxymethylfurfural at industrial current density
Sc-NiFe-LDH catalyzed electrooxidation of HMF to FDCA, achieving the FDCA faradic efficiency and selectivity of 96.5% and 99.5%, respectively, at a current density of >600 mA cm−2.
Nanoscale, 2025,17, 3114-3122
https://doi.org/10.1039/D4NR04389H
High strength chitosan-based nanocomposites with aligned nanosheets and crosslinked networks
The prepared nanocomposite films have dense covalent crosslinked networks and highly aligned nanosheets, which endows them with high mechanical properties, which are much higher than those of all other chitosan-based composites films.
Nanoscale, 2025,17, 3105-3113
https://doi.org/10.1039/D4NR04492D
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Synthetic control over lattice strain in trimetallic AuCu-core Pt-shell nanoparticles
Lattice strain in trimetallic Pt-shell Au1−xCux-core nanoparticles was tuned from tensile strain to compressive strain by increasing the Cu fraction in the AuCu-core.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04424J
Copper nanoclusters with aggregation-induced emission: an effective photodynamic antibacterial agent for treating bacteria-infected wounds
Highly luminescent Cu NCs with AIE as photodynamic antimicrobial agents were synthesized and they exhibited exceptional photodynamic bacterial inactivation in vitro, alongside effective treatment of bacteria-infected wounds in vivo.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04718D
Changing the amyloid nucleation process using small molecules and substrates: a way to build two-dimensional materials
The assembly of two-dimensional (2D) peptide materials on substrates with the control of FG small molecules
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04624B
Encapsulated ruthenium sites in reaction microenvironment-regulated UiO-66 for stable acetylene hydrochlorination
We employed an encapsulation strategy and channel regulation for Ru sites to enhance the stability and activity in acetylene hydrochlorination.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04506H
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Doping Gd16 nanoclusters for expanded optical properties and thermometry applications
We achieved green–red color-tunable luminescence by controlling the doping of Tb3+ and Eu3+ ions in Gd16 clusters and attained a high relative sensitivity of up to 4.6% K−1 in the as-doped Gd15Tb1−xEux (x = 0.8).
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04779F
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A high sensitivity prostate-specific antigen SERS detection platform based on laser resonance nanoparticles
An immunoassay based on SERS was established using antibody magnetic beads and SERS nanotags. This method has the advantages of simple operation, high sensitivity, fast (10 minutes) detection, low cost and portability.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04510F
Unraveling the Infrared Detection Properties of Bi2Te3 Depending on Thickness from Semiconductor to Metal Surface States
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05067C
Defect passivation engineering of chalcogenide quantum dots via in situ fluorination treatment
Efficient carrier transport through reducing the traps in chalcogenide quantum dots (QDs) is crucial for their application in optoelectronic devices.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04410J
Construction of bimetallic oxy-hydroxides based on Ni(OH)2 nanosheets for sensitive non-enzymatic glucose detection via electrochemical oxidation and incorporation
Bimetallic oxy-hydroxides based on Ni(OH)2 nanosheets ((CoNi)Ox/Ni(OH)2@NF) were prepared by an electrochemical oxidation and incorporation method as high performance non-enzymatic sensors for glucose detection.
Nanoscale, 2025,17, 2589-2598
https://doi.org/10.1039/D4NR04342A
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Facet-controlled electrosynthesis of nanoparticles by combinatorial screening in scanning electrochemical cell microscopy
SECCM allows screening of facet-controlled electrodeposition of nanoparticles.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04564E
Unveiling the inhibition mechanism of host-defense peptide cathelicidin LL-37 on the amyloid aggregation of the human islet amyloid polypeptide
The host-defense peptide cathelicidin LL37 inhibits the amyloid aggregation of human islet amyloid polypeptides by hydrophobic associations and pi–pi interactions.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05075D
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What makes β-NaYF4:Er3+,Yb3+ such a successful luminescent thermometer?
The upconversion phosphor β-NaYF4:Er3+,Yb3+ is one of the primary working horse examples for ratiometric luminescent Boltzmann thermometry. But why? Theoretical arguments are used in this work to unravel that recorded success.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04392H
Mitochondria-targeting nanostructures from enzymatically degradable fluorescent amphiphilic polyesters
pH-responsive aqueous nanoassembly from a fluorescent neutral polyester selectively targets mitochondria in cancer cells over non-cancerous cells due to positive charge gain, while similar assemblies from cationic polyesters show no such selectivity.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04696J
Boosting Cu ion capture in high-salinity environments with amino-functionalized millispheres
This study demonstrates the development of amino-functionalized chloromethylated polystyrene (EDA@CMPS) millispheres that exhibit enhanced Cu ion adsorption in saline environments through salt-promoted protonation of amino groups.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04517C
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Preparation of bovine serum albumin nanospheres via desolvation: a study of synthesis, characterization, and aging
Bovine serum albumin nanoparticles synthesized via a modified desolvation method exhibit superior long-term stability in aqueous dispersion. Glucose investigated as a “green” alternative crosslinker.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04682J
A ferroelectrically modulated ultrasensitive two-dimensional perovskite phototransistor with zero-gate-bias
A gate-bias-free perovskite phototransistor with ultrasensitive optoelectronic performances is achieved through a high-capacity nonvolatile ferroelectric-gating.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04910A
Built-in electric field in the Mn/C60 heterojunction promotes electrocatalytic nitrogen reduction to ammonia
The built-in electric field in the Mn/C60 heterostructure optimized the adsorption energy of the key intermediate *NH–*NH2 and reduced the free energy barrier for the third hydrogenation step, which enhanced the intrinsic activity of the NRR.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04496G
Cleavable energy transfer labeled oligonucleotide probe for enhanced isothermal amplification detection and nano digital chip-based readout
We present a novel energy transfer-labeled oligonucleotide probe designed to enhance the sensitivity and specificity of LAMP assay for HPV 16 detection. Our approach achieves a detection limit of 1 fM and spans a dynamic range of five orders of magnitude.
Nanoscale, 2025,17, 1381-1391
https://doi.org/10.1039/D4NR03142C
Nitrogen-doped nanocarbon as a metal-free catalyst for CO2 hydroboration
The unprecedented catalytic performance of a metal-free N-doped nanocarbon catalyst in CO2 hydroboration is reported with the catalytic mechanism uncovered.
Nanoscale, 2025,17, 1392-1399
https://doi.org/10.1039/D4NR04225E
A 3D mixed ion-electron conducting framework for dendrite-free lithium metal anodes
A mixed ion-electron conducting framework, LLTO@CNT, was designed for lithium metal batteries with uniform Li deposition and long cycling stability.
Nanoscale, 2025,17, 1282-1288
https://doi.org/10.1039/D4NR04455J
A high-efficiency and long-cycling aqueous indium metal battery enabled by synergistic In3+/K+ interactions
The synergistic K+/In3+ interactions lead to a high-performance aqueous indium metal battery with high efficiency and long cycling life.
Nanoscale, 2025,17, 855-863
https://doi.org/10.1039/D4NR02905D
A flexible and energy independent fluorescence radiation fiber film dosimeter fabricated by electrostatic spinning
This article proposes a flexible and energy independent fluorescence radiation fiber film dosimeter fabricated by electrostatic spinning, providing a candidate material for wearable visual dosimeters for X-ray detection in the range of 0–350 Gy.
Nanoscale, 2025,17, 846-854
https://doi.org/10.1039/D4NR03392B
Densely distributed Co onto carbon-layer-coated flower-like Ni/Al2O3 and its tailored integration into a stirrer for multiple catalytic degradation and solar-powered water evaporation
Multiple functional tailored materials have shown great potential for both pollutant degradation and freshwater recovery.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04430D
Preceramic polymer-hybridized phenolic aerogels and the derived ZrC/SiC/C ceramic aerogels with ultrafine nanocrystallines
This work provides a facile approach to fabricate hybrid phenolic aerogels and derived ZrC/SiC/C ceramic aerogels, which target on applications for extreme environments in aerospace field.
Nanoscale, 2025,17, 230-242
https://doi.org/10.1039/D4NR03470H
About this collection
Nanoscale is proud to present this themed collection highlighting 2025’s rising stars of nanoscience and nanotechnology research, which gathers the very best work from researchers in the early stages of their independent career.
Each contributor was recommended by experts in their fields for carrying out work with the potential to influence future directions in nanoscience and nanotechnology. Congratulations to all the featured researchers on their important work in the field so far!