Themed collection Recent Review Articles

Fullerene-driven photocarrier processes in perovskite solar cells: recent advances
Recent advances in understanding photocarrier dynamics of fullerenes in PSCs, focusing on charge transport, interfacial interactions, and the impact of functionalized derivatives on efficiency and stability.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01894C
Fabrication of MXene films through various techniques: a mini review
MXenes are 2D materials with high conductivity and tunable surfaces, ideal for energy storage and flexible electronics.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01272D
Mechanistic insights and rational catalyst design in NOx electroreduction
This review integrates theoretical and computational advances to identify active sites and key intermediates in NOx electroreduction, offering mechanistic insights and guiding principles for selective ammonia synthesis.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01682G

Photoluminescence fluctuations in single perovskite nanocrystals: structural, environmental and ligand effect
This review discusses key factors influencing photoluminescence fluctuations of single perovskite nanocrystals and highlights surface passivation strategies to enhance their stability.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01778E
The application prospect of metal/metal oxide nanoparticles in the treatment of intervertebral disc degeneration
This review highlights the therapeutic potential of metal-based and metal oxide nanoparticles in IVDD by leveraging their antioxidant, anti-inflammatory, and microenvironment-modulating properties to enhance tissue repair. The ToC was created in BioRender. Zhang, L. (2025) https://BioRender.com/6fzdcqv.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05504G

Iron-based nanozymes induced ferroptosis for tumor therapy
This review highlights iron-based nanozymes including iron oxides, single-atom nanozymes, and MOFs that induce ferroptosis via ROS generation and Fenton chemistry, achieved by POD-, CAT-, OXD- and SOD-like activities.
Nanoscale, 2025,17, 14103-14117
https://doi.org/10.1039/D5NR00880H
Stimulus-responsive nanomaterials for ocular antimicrobial therapy
This review highlights recent stimulus-responsive antimicrobial nanotherapeutics for ocular infections, focusing on their design, progress, and advantages/limitations.
Nanoscale, 2025,17, 13653-13667
https://doi.org/10.1039/D4NR05462H

Mechanism of methane activation and graphene growth on oxide ceramics
Mechanisms of graphene growth via chemical vapor deposition on oxide ceramics such as Al2O3, MgO, CaO, and SiO2 are discussed, with a focus on substrate-specific methane activation processes, toward versatile three-dimensional graphene synthesis.
Nanoscale, 2025,17, 13646-13652
https://doi.org/10.1039/D5NR00569H
A review on the insights into redox-based regeneration strategies for LiFePO4 batteries
This review systematically compiles studies on redox reactions during SLFP regeneration, which are crucial for enhancing the understanding the regeneration of SLFP batteries.
Nanoscale, 2025,17, 12048-12064
https://doi.org/10.1039/D4NR04671D
Polymer additives in liquid electrolytes for advanced lithium batteries
This review focuses on the recent application progress of polymer additives in liquid electrolytes for lithium batteries.
Nanoscale, 2025,17, 11275-11292
https://doi.org/10.1039/D5NR00470E

Recent progress of noble metal-based nanozymes: structural engineering and biomedical applications
This review highlights the recent progress in structural engineering of noble metal-based nanozymes and their enzyme-like properties in various enzyme-mimicking reactions and diverse biomedical applications.
Nanoscale, 2025,17, 10557-10580
https://doi.org/10.1039/D4NR05514D

Spin effects in metal halide perovskite semiconductors
This review explores the spin effects in both achiral and chiral metal halide perovskites and their opto-spintronic applications.
Nanoscale, 2025,17, 9895-9906
https://doi.org/10.1039/D5NR00127G
Flexible fibrous electrodes for implantable biosensing
This review explores advancements, applications, challenges, and future prospects of flexible fibrous electrodes for implantable biosensing, highlighting their potential in biomedical monitoring and human–machine interfaces. Images reproduced with permission, full details in paper.
Nanoscale, 2025,17, 9870-9894
https://doi.org/10.1039/D4NR04542D
Biomimetic ion channels with subnanometer sizes for ion sieving: a mini-review
The ion-selective transport property of biological systems has inspired the development of biomimetic ion channels. This mini-review highlights the mechanisms, recent fabrication strategies and applications of biomimetic ion channels.
Nanoscale, 2025,17, 9021-9039
https://doi.org/10.1039/D5NR00758E
Smart MXene-based microrobots for targeted drug delivery and synergistic therapies
This review emphasizes the groundbreaking potential of MXene-based microrobots in developing targeted drug delivery and synergistic therapeutic approaches.
Nanoscale, 2025,17, 9040-9056
https://doi.org/10.1039/D4NR05160B
Cu-based bimetallic catalysts for electrochemical CO2 reduction: before and beyond the tandem effect
Cu-based bimetallic catalysts show enhanced electrochemical CO2 reduction performance via the tandem effect. This review traces their progress, highlighting design advances, mechanisms, and challenges to guide efficient CO2 conversion.
Nanoscale, 2025,17, 9057-9071
https://doi.org/10.1039/D4NR04790G
Functionalization of rod-shaped plant viruses for biomedical applications
This review explores the development of biomedical nanomaterials based on rod-shaped plant viruses, providing insights into the design of innovative biomaterials for applications related to drug delivery, bioimaging and immune-therapy. Created in https://BioRender.com.
Nanoscale, 2025,17, 9072-9085
https://doi.org/10.1039/D4NR05354K

Hydrogen bubble evolution and its induced mass transfer on zinc electrodes in alkaline and neutral media
Hydrogen bubble evolution presents both challenges and opportunities in Zn-based batteries. While bubble evolution induces electrode instability and dendrite formation, it can also optimize mass transfer through controlled fluid dynamics.
Nanoscale, 2025,17, 8453-8465
https://doi.org/10.1039/D4NR05108D

Characterisation of polymeric nanoparticles for drug delivery
Polymeric nanoparticles represent an innovative approach to drug delivery, particularly for addressing complex diseases like cancer.
Nanoscale, 2025,17, 7738-7752
https://doi.org/10.1039/D5NR00071H
External strategies for enhanced sensing performance of self-powered polyvinylidene fluoride-based sensors
External strategies such as electrode design, stress/heat transfer improvements, microstructure optimization, and multifunctional synergy show great potential for improving sensing performance of PVDF-based sensors. Images reproduced with permission, full details in paper.
Nanoscale, 2025,17, 6981-6992
https://doi.org/10.1039/D4NR05200E

Sustainable nanofibrous membranes for air filtration, water purification and oil removal
The increasing demand for sustainable solutions to address environmental and energy challenges has driven the development of advanced materials. This paper highlights recent advancements in the development of sustainable nanofibrous membranes.
Nanoscale, 2025,17, 6427-6447
https://doi.org/10.1039/D4NR04673K
Recent advances in multimodal mechanoluminescent sensors enabled by nanostructure design
Multifunctional coupling and signal decoupling achieved through nanostructure and supramolecule design, enable multimodal mechanoluminescent materials to play an increasingly important role in interdisciplinary applications and cutting-edge fields.
Nanoscale, 2025,17, 6414-6426
https://doi.org/10.1039/D4NR04875J
Multifunctional DNA nanomaterials: a new frontier in rheumatoid arthritis diagnosis and treatment
DNA nanomaterials offer promising advancements in addressing the challenges of rheumatoid arthritis (RA) through targeted drug delivery, biomarker detection, and therapeutic innovation.
Nanoscale, 2025,17, 4974-4999
https://doi.org/10.1039/D4NR04013A
Colloidal semiconductor quantum shells for solution-processed laser applications
Laser diodes based on solution-processed semiconductor quantum dots (QDs) present an economical and color-tunable alternative to traditional epitaxial lasers.
Nanoscale, 2025,17, 3698-3707
https://doi.org/10.1039/D4NR04653F
Leveraging the dual role of ROS in liver diseases with nanomaterials: clearing and amplifying for therapy
The dual role of ROS in liver diseases, and the potential of nanomaterials with catalytic activity for therapeutic applications are examined.
Nanoscale, 2025,17, 3688-3697
https://doi.org/10.1039/D4NR04469J
NIR-II upconversion nanomaterials for biomedical applications
This review provides a comprehensive overview of recent biomedical applications of upconversion nanomaterials specifically within the near-infrared two-region (NIR-II) window (1000–1700 nm).
Nanoscale, 2025,17, 2985-3002
https://doi.org/10.1039/D4NR04445B
Mathematically inspired structure design in nanoscale thermal transport
Mathematically inspired structure design has emerged as a powerful approach for tailoring material properties, especially in nanoscale thermal transport, with promising applications both within this field and beyond.
Nanoscale, 2025,17, 3003-3013
https://doi.org/10.1039/D4NR04385E

Advances in integrated power supplies for self-powered bioelectronic devices
The emerging integrated power supplies for self-powered bioelectronic devices over the past few years are summarized. Additionally, the challenges and future perspectives in self-powered device design and manufacturing are also indicated.
Nanoscale, 2025,17, 2423-2437
https://doi.org/10.1039/D4NR04645E

Design strategies and performance enhancements of PVDF-based flexible electrolytes for high-performance all-solid-state lithium metal batteries
Lithium metal is considered one of the most promising anode materials for lithium batteries due to its high theoretical specific capacity (3860 mA h g−1) and low redox potential (−3.04 V).
Nanoscale, 2025,17, 2408-2422
https://doi.org/10.1039/D4NR04583A
Organic semiconductor bulk heterojunctions for solar-to-chemical conversion: recent advances and challenges
This minireview highlights recent progress in BHJ-based photoelectrochemical cells and photocatalysts for solar-to-chemical conversions.
Nanoscale, 2025,17, 1889-1921
https://doi.org/10.1039/D4NR03938F
Chiral nanomaterials as vaccine adjuvants: a new horizon in immunotherapy
Chiral nanomaterials are emerging as a promising class of vaccine adjuvants with the potential to significantly enhance vaccine efficacy, especially in the context of cancer immunotherapy.
Nanoscale, 2025,17, 1932-1935
https://doi.org/10.1039/D4NR03542A

Advances in simulating dilute alloy nanoparticles for catalysis
Dilute and single-atom alloy catalysts have attracted tremendous attention in heterogeneous catalysis. Herein, we discuss recent progress on simulating their stability and catalytic behavior.
Nanoscale, 2025,17, 1936-1953
https://doi.org/10.1039/D4NR03761H
Near-infrared circularly polarized luminescence enabled by chiral inorganic nanomaterials
We summarize the latest developments in NIR-CPL generated by chiral inorganic nanomaterials and provide new perspectives for constructing NIR-CPL materials and developing new applications for chiral nanomaterials.
Nanoscale, 2025,17, 1922-1931
https://doi.org/10.1039/D4NR03743J
Bioinspired solid-state nanochannels for molecular analysis
Solid-state nanochannel sensors consisting of recognition elements and nanochannels are capable of detecting a wide range of small molecules including gas molecules, drug molecules and biomolecules.
Nanoscale, 2025,17, 1225-1237
https://doi.org/10.1039/D4NR03711A
Unveiling nanoparticle–immune interactions: how super-resolution imaging illuminates the invisible
This mini-review focuses on how super-resolution techniques uncover the detailed interactions between nanoparticles and immune cells.
Nanoscale, 2025,17, 1213-1224
https://doi.org/10.1039/D4NR03838J

Chirality generation on carbon nanosheets by chemical modification
Chirality is an intriguing property of molecules, and exciting area of study involves the generation of chirality in nanographenes (NGs), also known as graphene quantum dots.
Nanoscale, 2025,17, 774-787
https://doi.org/10.1039/D4NR02952F
Multi-scale assembly strategies driven by arene–perfluoroarene interaction: molecular design of functional materials
The arene–perfluoroarene force enables coassemblies with pronounced optical properties, which provide protocols for fabricating chiroptical materials.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01626F
Optoelectronic MXene quantum dots: frontiers in sensor technology for next-generation diagnostics and environmental monitoring
MXene QDs are illustrated, showcasing their synthesis, properties, and emerging applications in next-generation diagnostics and environmental monitoring.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00854A
From nature to nanotechnology: the synergistic integration of biomimetic nanomaterials and conductive hydrogels for next-generation applications
Biomimetic nanomaterials (0D, 1D, and 2D nanomaterials) for the functional design and applications of double-network conductive hydrogels. Images adapted from Servier Medical Art (https://smart.servier.com/), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/).
Nanoscale, 2025,17, 14558-14586
https://doi.org/10.1039/D5NR01248A
Gallium-based nano-liquid metals enabled antimicrobial mechanisms and biomedical applications
This review summarizes the unique role of novel gallium-based nano-liquid metals in antibacterial applications, focusing on their distinctive activities and underlying antibacterial mechanisms. The graphical abstract was created in BioRender. R, z. (2025) https://BioRender.com/v96z429.
Nanoscale, 2025,17, 14441-14457
https://doi.org/10.1039/D5NR00406C

Current state and potential of polymersomes as ocular drug delivery systems
Polymersomes offer tuneable membrane and release traits, with mobility and ability to traverse barriers, making them a promising ocular delivery alternative. Images adapted from Servier Medical Art (https://smart.servier.com/), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/)
Nanoscale, 2025,17, 14458-14476
https://doi.org/10.1039/D5NR01273B
Computational modelling of nanoparticle catalysis
An overview of progress in computational nanocatalysis, including methods for modelling nanoparticle catalysis and computational analysis of their structure and catalytic activity.
Nanoscale, 2025,17, 14491-14520
https://doi.org/10.1039/D4NR04364B
Hydrogel–exosome complexes: a novel strategy for cardiovascular regeneration
Cardiovascular disease (CVD) remains one of the leading causes of high mortality and morbidity worldwide, posing a substantial threat to global health.
Nanoscale, 2025,17, 14477-14490
https://doi.org/10.1039/D5NR00892A
Recent progress of carbon dots in the theranostics of cardiovascular and cerebrovascular diseases
We summarize recent advances in the theranostics of cardiovascular and cerebrovascular diseases using carbon dots (CDs), and introduce the specific application performance of CDs.
Nanoscale, 2025,17, 14521-14557
https://doi.org/10.1039/D5NR01322D
Advances in nanomaterial thin-film temperature sensors: materials and applications
This review provides a comparative overview of thin-film temperature sensors based on five major material groups, highlighting their mechanisms, strengths, limitations, and integration into wearable, e-skin, and robotic applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01099C
Quantum Dots as Multifunctional Therapeutic Agents: Synergistic Antitumor and Antimicrobial Mechanisms
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00606F
Bibliometric review on flexible pressure sensor design strategies
This review summarizes advancements in flexible pressure sensor design, including materials, devices, algorithm design, and systems, using bibliometric methods. The materials used in the system section are sourced from Vecteezy (Vecteezy.com).
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00394F

Advancing extracellular vesicle production: improving physiological relevance and yield with 3D cell culture
3D cell cultures produce higher EV yields, with comparable or more physiologically relevant morphology, enriched cargo, and enhanced functionality. However, each model presents distinct strengths and limitations that must be carefully considered.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00707K
Research progress on functional polymer solid electrolytes for lithium batteries
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01513H

Advancements in DNA-PAINT: applications and challenges in biological imaging and nanoscale metrology
DNA-PAINT applications are guiding new advancements in a virtuous cycle that benefits bioimaging and nanometrology.
Nanoscale, 2025,17, 14016-14034
https://doi.org/10.1039/D4NR04544K
Advances in multimodal electrohydrodynamic printing for high-resolution sensor fabrication: mechanisms, materials, and applications
Schematic diagram of electrohydrodynamic printing of various structures and its applications in sensor fabrication. Images reproduced with permission, full details in paper.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01375E
Quantum and critical Casimir effects: bridging fluctuation physics and nanotechnology
This review sheds light on the primary representation of fluctuation-induced forces, the Casimir effect, both in its classical (critical) and quantum expressions, highighting their role on the development of nanoscale devices.
Nanoscale, 2025,17, 13982-13997
https://doi.org/10.1039/D5NR01288K
Graphene quantum dots induced performance enhancement in memristors
This review summarizes the recent advances of GQD-based memristors mainly in terms of GQD features, memristive mechanisms, and application fields, thereby providing insights for the development and design of GQD-based memristors.
Nanoscale, 2025,17, 14082-14102
https://doi.org/10.1039/D5NR00597C
Recent advances in the synthesis and passivation of pure bromide-based perovskite nanoplatelets
The peculiar properties of low-dimensional inorganic lead halide perovskite materials have triggered the attention of researchers in the past decade. Variation of bandgap energy with the number of layers of the perovskite nanoplatelet.
Nanoscale, 2025,17, 14035-14081
https://doi.org/10.1039/D5NR01215E
Recent advances of metal cluster-based SERS probes for biomedical applications
This review summarizes the latest progress in the field of SERS, including advanced substrate materials and their enhancement mechanisms, with an emphasis on metal cluster-based SERS probes and their biomedical applications.
Nanoscale, 2025,17, 13998-14015
https://doi.org/10.1039/D5NR01131K
Two-dimensional anisotropic semiconductors: from structure and properties to device applications
This review systematically summarizes the electronic band structures, optical properties and device applications of 2D anisotropic semiconductors.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01305D
A review: metal and metal oxide nanoparticles for environmental applications
Environmental applications of metal and metal oxide nanoparticles primarily comprise contaminant adsorbents, catalysts, and sensors for hazardous substances, etc.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01973G
Engineering tough, energy-dissipating soft materials via sacrificial chemical bonds
This review outlines the chemical toolkit for energy-dissipating sacrificial bonds by surveying recent (post-2017) developments in tough, impact-resistant soft materials.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00018A
Recent Progress in Polyaniline-based Catalysts for Electrochemical Energy Conversion
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00966A
Electrocatalytic Nitrogen Reduction: Mechanisms, System-Level Optimization, and Future Perspectives
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01582K
Interplay between the shape anisotropy and optical properties of Cu- and Ag-based ternary and quaternary chalcogenide nanocrystals
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01376C
Nanochemistry advancing photofertilizer for plant research
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00906E
Materials, Mechanisms, and Emerging Applications of Electrochromics
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR02098G
Metal-based micro/nanomaterials for hydrogen therapy and their biomedical applications
This review comprehensively explores the biological effects of hydrogen, hydrogen release mechanisms, synthesis methods, and biomedical applications of hydrogen-releasing metal-based micro/nanomaterials.
Nanoscale, 2025,17, 13594-13621
https://doi.org/10.1039/D5NR00271K
Optimization of the hole-injection layer for quantum dot light-emitting diodes
This review summarizes the optimization strategies for the HILs in QLEDs, focusing on the design of single HILs, dual HILs, and doped HILs. Additionally, treatment methods that can further optimize the interfacial properties are discussed.
Nanoscale, 2025,17, 13581-13593
https://doi.org/10.1039/D5NR01052G

Material characterization methods for investigating charge storage processes in 2D and layered materials-based batteries and supercapacitors
An overview of the characterization techniques for probing charge storage mechanisms of 2D and thin-layered materials as electrodes in electrochemical energy storage systems.
Nanoscale, 2025,17, 13531-13560
https://doi.org/10.1039/D5NR00649J
Challenges and future prospects of the 2D material-based composites for microwave absorption
2D materials, including graphene, boron nitride (BN), and MXene, have attracted wide attention in microwave absorption due to their unique lamellar structure, large specific surface area, low density, and good thermal and chemical stability.
Nanoscale, 2025,17, 13622-13645
https://doi.org/10.1039/D5NR00925A
Metal–organic frameworks for NH3 adsorption and separation
MOFs are promising NH3 adsorbent candidates due to their highly tunable structure and functionality, which can precisely match the characteristics required for NH3 adsorbents in multiple application scenarios.
Nanoscale, 2025,17, 13561-13580
https://doi.org/10.1039/D5NR00651A
Polymeric nanoparticle synthesis for biomedical applications: advancing from wet chemistry methods to dry plasma technologies
This review critically compares wet chemical and plasma polymerization methods for polymeric nanoparticle synthesis, highlighting plasma polymerization as a dry, scalable platform with insights into clinical translation and commercialization.
Nanoscale, 2025,17, 13020-13056
https://doi.org/10.1039/D5NR00436E
Challenges, opportunities, and roadmap for ionic liquid-based electrolytes in advancing energy storage devices
This review offers a thorough and authoritative overview of research advancements in the field of ionic liquid-based electrolytes with an emphasis on Li-ion batteries and supercapacitors.
Nanoscale, 2025,17, 13121-13144
https://doi.org/10.1039/D5NR00522A
About this collection
In addition to high impact and high quality research across nanoscience & nanotechnology, Nanoscale publishes topical review articles. Reviews will be added to this webpage as soon as possible after publication.