Themed collection International Conference on Polyphenols and Health (ICPH2022) special collection

Exosomes direct and indirect roles mediating (poly)phenol effects.

This randomized, double-blind, placebo-controlled trial showed that blueberries improve endothelial function through reduced oxidative stress in postmenopausal women with above-normal blood pressure.

CGA plus EGCG improve the gut barrier injury in aging mice induced by D-galactose through modulating the tight junctions, inflammation, oxidative stress and dysbiosis.

Walnut polyphenols and urolithin A up-regulate PKA/CREB/BDNF signaling pathway which is required for their neuroprotective effects against oxidative stress and may underlie their health benefits on the brain.

Original Mediterranean Diet and Altered Mediterranean Diet were associated with positive mood when adjusted for sex and age in healthy people. Plant-based Diet Index was only associated with children’s positive mood.

This study compared the agreement between a food frequency questionnaire and a 7-day food diary in assessing (poly)phenol intake and explore their associations with the urinary and plasma (poly)phenol metabolites.

Multiple sclerosis (MS) is a neurodegenerative disease that progressively decreases the muscular and functional capacity.

Supplementation with Rooibos extract modulated metabolic markers, adipocyte size and adipose stem cell (ASC) function in rats, under different dietary conditions. This is the first in vivo/ex vivo study to demonstrate effects of Rooibos on ASCs.

Treatment of anxiety and depression predominantly centres around pharmacological interventions, which have faced criticism for their associated side effects, lack of efficacy and low tolerability.

Natural polyphenols are plant metabolites exhibiting a broad range of biological activities.

Purified recombinant enzymes are efficient at hydrolyzing microbial (poly)phenol metabolite phase II conjugates, and hence, can be used to accurately quantify them using unconjugated analytical standards.

T2DM individuals exhibit macro- and microvascular dysfunction that is pronounced in the legs. Cocoa acutely increases endothelial function of the brachial and the femoral arteries and dilation of microvasculature in the feet of T2DM and healthy individuals.

(−)-Epicatechin exerts complex genomic modifications in the hippocampus, counteracting changes driven by consumption of the high fat diet and/or associated obesity.

Upper tract gastrointestinal digestion unlocks the ability of cocoa and coffee bioactives to inhibit bacterial TMA formation.

In this contribution we show that 5-caffeoyl quinic acid reduces the affinity of the Coronavirus 2 Spike protein to the human ACE-2 receptor promising dietary prevention or slow-down of the SARS-CoC-2 pandemic.

This study provides evidence that consuming flavonoid-rich food may be protective against type 2 diabetes (T2DM) through mechanisms related to better glucose tolerance and insulin sensitivity.