Themed collection Electrochemically driven catalytic organic transformations

Herein, an overview of the evolution of electrochemical C–H annulations with alkynes for the construction of heterocycles is provided, with a topical focus on the underlying mechanism manifolds.

This review summarizes recent advances in the electrochemically enabled construction of indoles from non-indole-based precursors and their underlying mechanisms.

Peroxodicarbonate, accessible from direct anodic conversion of alkali carbonates, has experienced a renaissance in the past two decades. An overview of its history, synthesis, characteristics and reactivity is provided.

An inner-sphere approach to aldehyde electrohydrogenation leads to a key nickeloxirane. Protonation of that intermediate yields the hydrogenation products, but electrocatalysis remains challenging.

The work demonstrates the successful merger of electrochemistry with asymmetric iminium ion organocatalysis.

A dual transition metal-catalyzed electrophotochemical deconstructive arylation of cyclic alcohols has been developed, providing an efficient and sustainable method for the synthesis of distally arylated ketones.

A bio-inspired electrooxidation and acid-controlled heterodimerization of pyrrolidine-1-carboxamides was developed. Acid choice dictates endo/exo dimer formation, with chiral phosphoric acid yielding enantioenriched exo-dimers.

Electrochemical operando Raman spectroscopy is able to elucidate the reaction mechanism of the electrooxidative sesamol dimerization reaction.

Electroorganic synthesis has become an exciting tool for the asymmetric conversion of pro-chiral compounds.

Following Ni-catalysed Suzuki–Miyaura cross coupling reactions, Ni is electrochemically removed on to the cathode, offering potential for recovery and reuse.

We herein reported a tunable electrochemical diverse sulfurization of sulfoxonium ylides with disulfides for the synthesis of sulfursulfoxonium ylides and 1,3-dithioketals.

Efficient and selective electrochemical oxidation of biomass-derived ethylene glycol to lactic acid is achieved over nickel catalyst by controlling the pH of the electrolyte solution.

A mild and efficient electrochemical method for radical addition, cyclization, and migration reaction was described in this work.

A novel electrochemical multicomponent reaction (e-MCR) synthesizes N-substituted S-thiocarbamate derivatives from isocyanides, thiols, and carboxylic acids via a difunctionalization and Mumm rearrangement cascade.

A simple and scalable electrosynthesis of a broad scope of 4-hydroxy-1,4-benzoxazin-3-ones was developed by simple reduction of inexpensive nitroarenes.

The α-C(sp³)–H difluoroalkylation of tetrahydroisoquinolines and isochromans via electrochemical oxidation was developed using organozinc reagents to achieve a broad substrate scope under mild reaction conditions.

The electro-generation of acyl radicals from both aromatic and aliphatic aldehydes is a synthetic challenge. We addressed this challenge by merging electro-oxidation and a quinuclidine-mediated HAT strategy.

Titanium electrodes bearing the naturally-forming native oxide coating are competent for the electroreduction of oxalic acid to glyoxylate and glycolate.

An organophotoelectrocatalytic method for the C(sp²)–H alkylation of heteroarenes with unactivated C(sp³)–H compounds via dehydrogenation cross-coupling was developed.

Herein, an electrochemical approach toward the ring opening functionalization of methylenecyclopropanes (MCPs) via C–C bond cleavage in the presence of alcohols is reported.

The development of an electrochemical cobalt catalyzed C–Cl bond activation at room temperature for the nucleophilic addition of aryl and vinyl chlorides to α-ketoamides and the extension to an enantioselective electrochemical reaction is described.