Themed collection Recent Review Articles

g-C3N5-based Photocatalysts for Energy and Environmental Applications: Insights into Properties, Structural Modifications, Challenges, and Future Directions
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR02485D

Challenges and strategies for first-principles simulations of two-dimensional magnetic phenomena
This review introduces key concepts and tools for modelling 2D magnets with DFT, covering magnetism basics, challenges like spin order, and methods to extract Hamiltonian parameters and critical temperatures for various anisotropies.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05503A

Advances in carbon nanomembranes for separation: from free-standing films to composite structures
This work reviews carbon nanomembranes (CNMs) from self-assembled monolayers to composite membranes, focusing on their development and potential in separation applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05361C
Fullerene-driven photocarrier processes in perovskite solar cells: recent advances
Recent advances in understanding photocarrier dynamics of fullerenes in PSCs, focusing on charge transport, interfacial interactions, and the impact of functionalized derivatives on efficiency and stability.
Nanoscale, 2025,17, 15648-15675
https://doi.org/10.1039/D5NR01894C

Photoluminescence fluctuations in single perovskite nanocrystals: structural, environmental and ligand effect
This review discusses key factors influencing photoluminescence fluctuations of single perovskite nanocrystals and highlights surface passivation strategies to enhance their stability.
Nanoscale, 2025,17, 15617-15627
https://doi.org/10.1039/D5NR01778E
Mechanistic insights and rational catalyst design in NOx electroreduction
This review integrates theoretical and computational advances to identify active sites and key intermediates in NOx electroreduction, offering mechanistic insights and guiding principles for selective ammonia synthesis.
Nanoscale, 2025,17, 15628-15647
https://doi.org/10.1039/D5NR01682G
Fabrication of MXene films through various techniques: a mini review
MXenes are 2D materials with high conductivity and tunable surfaces, ideal for energy storage and flexible electronics.
Nanoscale, 2025,17, 15676-15689
https://doi.org/10.1039/D5NR01272D
The application prospect of metal/metal oxide nanoparticles in the treatment of intervertebral disc degeneration
This review highlights the therapeutic potential of metal-based and metal oxide nanoparticles in IVDD by leveraging their antioxidant, anti-inflammatory, and microenvironment-modulating properties to enhance tissue repair. The ToC was created in BioRender. Zhang, L. (2025) https://BioRender.com/6fzdcqv.
Nanoscale, 2025,17, 15605-15616
https://doi.org/10.1039/D4NR05504G

Iron-based nanozymes induced ferroptosis for tumor therapy
This review highlights iron-based nanozymes including iron oxides, single-atom nanozymes, and MOFs that induce ferroptosis via ROS generation and Fenton chemistry, achieved by POD-, CAT-, OXD- and SOD-like activities.
Nanoscale, 2025,17, 14103-14117
https://doi.org/10.1039/D5NR00880H
Stimulus-responsive nanomaterials for ocular antimicrobial therapy
This review highlights recent stimulus-responsive antimicrobial nanotherapeutics for ocular infections, focusing on their design, progress, and advantages/limitations.
Nanoscale, 2025,17, 13653-13667
https://doi.org/10.1039/D4NR05462H

Mechanism of methane activation and graphene growth on oxide ceramics
Mechanisms of graphene growth via chemical vapor deposition on oxide ceramics such as Al2O3, MgO, CaO, and SiO2 are discussed, with a focus on substrate-specific methane activation processes, toward versatile three-dimensional graphene synthesis.
Nanoscale, 2025,17, 13646-13652
https://doi.org/10.1039/D5NR00569H
A review on the insights into redox-based regeneration strategies for LiFePO4 batteries
This review systematically compiles studies on redox reactions during SLFP regeneration, which are crucial for enhancing the understanding the regeneration of SLFP batteries.
Nanoscale, 2025,17, 12048-12064
https://doi.org/10.1039/D4NR04671D
Polymer additives in liquid electrolytes for advanced lithium batteries
This review focuses on the recent application progress of polymer additives in liquid electrolytes for lithium batteries.
Nanoscale, 2025,17, 11275-11292
https://doi.org/10.1039/D5NR00470E

Recent progress of noble metal-based nanozymes: structural engineering and biomedical applications
This review highlights the recent progress in structural engineering of noble metal-based nanozymes and their enzyme-like properties in various enzyme-mimicking reactions and diverse biomedical applications.
Nanoscale, 2025,17, 10557-10580
https://doi.org/10.1039/D4NR05514D

Spin effects in metal halide perovskite semiconductors
This review explores the spin effects in both achiral and chiral metal halide perovskites and their opto-spintronic applications.
Nanoscale, 2025,17, 9895-9906
https://doi.org/10.1039/D5NR00127G
Flexible fibrous electrodes for implantable biosensing
This review explores advancements, applications, challenges, and future prospects of flexible fibrous electrodes for implantable biosensing, highlighting their potential in biomedical monitoring and human–machine interfaces. Images reproduced with permission, full details in paper.
Nanoscale, 2025,17, 9870-9894
https://doi.org/10.1039/D4NR04542D
Biomimetic ion channels with subnanometer sizes for ion sieving: a mini-review
The ion-selective transport property of biological systems has inspired the development of biomimetic ion channels. This mini-review highlights the mechanisms, recent fabrication strategies and applications of biomimetic ion channels.
Nanoscale, 2025,17, 9021-9039
https://doi.org/10.1039/D5NR00758E
Smart MXene-based microrobots for targeted drug delivery and synergistic therapies
This review emphasizes the groundbreaking potential of MXene-based microrobots in developing targeted drug delivery and synergistic therapeutic approaches.
Nanoscale, 2025,17, 9040-9056
https://doi.org/10.1039/D4NR05160B
Cu-based bimetallic catalysts for electrochemical CO2 reduction: before and beyond the tandem effect
Cu-based bimetallic catalysts show enhanced electrochemical CO2 reduction performance via the tandem effect. This review traces their progress, highlighting design advances, mechanisms, and challenges to guide efficient CO2 conversion.
Nanoscale, 2025,17, 9057-9071
https://doi.org/10.1039/D4NR04790G
Functionalization of rod-shaped plant viruses for biomedical applications
This review explores the development of biomedical nanomaterials based on rod-shaped plant viruses, providing insights into the design of innovative biomaterials for applications related to drug delivery, bioimaging and immune-therapy. Created in https://BioRender.com.
Nanoscale, 2025,17, 9072-9085
https://doi.org/10.1039/D4NR05354K

Hydrogen bubble evolution and its induced mass transfer on zinc electrodes in alkaline and neutral media
Hydrogen bubble evolution presents both challenges and opportunities in Zn-based batteries. While bubble evolution induces electrode instability and dendrite formation, it can also optimize mass transfer through controlled fluid dynamics.
Nanoscale, 2025,17, 8453-8465
https://doi.org/10.1039/D4NR05108D

Characterisation of polymeric nanoparticles for drug delivery
Polymeric nanoparticles represent an innovative approach to drug delivery, particularly for addressing complex diseases like cancer.
Nanoscale, 2025,17, 7738-7752
https://doi.org/10.1039/D5NR00071H
External strategies for enhanced sensing performance of self-powered polyvinylidene fluoride-based sensors
External strategies such as electrode design, stress/heat transfer improvements, microstructure optimization, and multifunctional synergy show great potential for improving sensing performance of PVDF-based sensors. Images reproduced with permission, full details in paper.
Nanoscale, 2025,17, 6981-6992
https://doi.org/10.1039/D4NR05200E

Sustainable nanofibrous membranes for air filtration, water purification and oil removal
The increasing demand for sustainable solutions to address environmental and energy challenges has driven the development of advanced materials. This paper highlights recent advancements in the development of sustainable nanofibrous membranes.
Nanoscale, 2025,17, 6427-6447
https://doi.org/10.1039/D4NR04673K
Recent advances in multimodal mechanoluminescent sensors enabled by nanostructure design
Multifunctional coupling and signal decoupling achieved through nanostructure and supramolecule design, enable multimodal mechanoluminescent materials to play an increasingly important role in interdisciplinary applications and cutting-edge fields.
Nanoscale, 2025,17, 6414-6426
https://doi.org/10.1039/D4NR04875J
Multifunctional DNA nanomaterials: a new frontier in rheumatoid arthritis diagnosis and treatment
DNA nanomaterials offer promising advancements in addressing the challenges of rheumatoid arthritis (RA) through targeted drug delivery, biomarker detection, and therapeutic innovation.
Nanoscale, 2025,17, 4974-4999
https://doi.org/10.1039/D4NR04013A
Colloidal semiconductor quantum shells for solution-processed laser applications
Laser diodes based on solution-processed semiconductor quantum dots (QDs) present an economical and color-tunable alternative to traditional epitaxial lasers.
Nanoscale, 2025,17, 3698-3707
https://doi.org/10.1039/D4NR04653F
Leveraging the dual role of ROS in liver diseases with nanomaterials: clearing and amplifying for therapy
The dual role of ROS in liver diseases, and the potential of nanomaterials with catalytic activity for therapeutic applications are examined.
Nanoscale, 2025,17, 3688-3697
https://doi.org/10.1039/D4NR04469J
NIR-II upconversion nanomaterials for biomedical applications
This review provides a comprehensive overview of recent biomedical applications of upconversion nanomaterials specifically within the near-infrared two-region (NIR-II) window (1000–1700 nm).
Nanoscale, 2025,17, 2985-3002
https://doi.org/10.1039/D4NR04445B
Mathematically inspired structure design in nanoscale thermal transport
Mathematically inspired structure design has emerged as a powerful approach for tailoring material properties, especially in nanoscale thermal transport, with promising applications both within this field and beyond.
Nanoscale, 2025,17, 3003-3013
https://doi.org/10.1039/D4NR04385E

Advances in integrated power supplies for self-powered bioelectronic devices
The emerging integrated power supplies for self-powered bioelectronic devices over the past few years are summarized. Additionally, the challenges and future perspectives in self-powered device design and manufacturing are also indicated.
Nanoscale, 2025,17, 2423-2437
https://doi.org/10.1039/D4NR04645E

Design strategies and performance enhancements of PVDF-based flexible electrolytes for high-performance all-solid-state lithium metal batteries
Lithium metal is considered one of the most promising anode materials for lithium batteries due to its high theoretical specific capacity (3860 mA h g−1) and low redox potential (−3.04 V).
Nanoscale, 2025,17, 2408-2422
https://doi.org/10.1039/D4NR04583A
Organic semiconductor bulk heterojunctions for solar-to-chemical conversion: recent advances and challenges
This minireview highlights recent progress in BHJ-based photoelectrochemical cells and photocatalysts for solar-to-chemical conversions.
Nanoscale, 2025,17, 1889-1921
https://doi.org/10.1039/D4NR03938F
Chiral nanomaterials as vaccine adjuvants: a new horizon in immunotherapy
Chiral nanomaterials are emerging as a promising class of vaccine adjuvants with the potential to significantly enhance vaccine efficacy, especially in the context of cancer immunotherapy.
Nanoscale, 2025,17, 1932-1935
https://doi.org/10.1039/D4NR03542A

Advances in simulating dilute alloy nanoparticles for catalysis
Dilute and single-atom alloy catalysts have attracted tremendous attention in heterogeneous catalysis. Herein, we discuss recent progress on simulating their stability and catalytic behavior.
Nanoscale, 2025,17, 1936-1953
https://doi.org/10.1039/D4NR03761H
Near-infrared circularly polarized luminescence enabled by chiral inorganic nanomaterials
We summarize the latest developments in NIR-CPL generated by chiral inorganic nanomaterials and provide new perspectives for constructing NIR-CPL materials and developing new applications for chiral nanomaterials.
Nanoscale, 2025,17, 1922-1931
https://doi.org/10.1039/D4NR03743J
Bioinspired solid-state nanochannels for molecular analysis
Solid-state nanochannel sensors consisting of recognition elements and nanochannels are capable of detecting a wide range of small molecules including gas molecules, drug molecules and biomolecules.
Nanoscale, 2025,17, 1225-1237
https://doi.org/10.1039/D4NR03711A
Unveiling nanoparticle–immune interactions: how super-resolution imaging illuminates the invisible
This mini-review focuses on how super-resolution techniques uncover the detailed interactions between nanoparticles and immune cells.
Nanoscale, 2025,17, 1213-1224
https://doi.org/10.1039/D4NR03838J

Chirality generation on carbon nanosheets by chemical modification
Chirality is an intriguing property of molecules, and exciting area of study involves the generation of chirality in nanographenes (NGs), also known as graphene quantum dots.
Nanoscale, 2025,17, 774-787
https://doi.org/10.1039/D4NR02952F
Biocomputing systems based on carbon materials and DNA
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR02383A
Polymeric nanoparticles for efficient nose-to-brain delivery
Brain disorders affect over one billion people globally, presenting significant challenges for effective treatment due to the limited drug bioavailability in the brain. The graphical abstract was created with BioRender.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00870K
Carbon dots: translating versatile physicochemistry into multidisciplinary application frameworks
This article systematically reviews the physical and chemical properties of carbon dots, especially optical, thermal, electrical, and interfacial features, and their applications in the field of biomedical engineering, energy and environment, etc.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01901J
Recent advances in nanozymes based on mesoporous materials for enhancing the performance of colorimetric biosensors: Applications and challenges
Nanozymes derived from mesoporous materials and their application in colorimetric sensing.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01374G
Advances in Microneedle Technology for Skin Wound Healing: Integrating Nanomaterials and Intelligent Drug Delivery Systems
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01953B
Recent advances in using severe plastic deformation for the processing of nanomaterials
Processing by severe plastic deformation (SPD) refers to imposing a high strain without producing any significant dimensional changes. This review summarizes the principles of SPD processing.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01886B
Recent progress in gemcitabine-loaded nanoparticles for pancreatic cancer therapy: a review
Gemcitabine-based nanodelivery strategies for pancreatic cancer include efficient carriers, combination therapies, and prodrug systems to enhance stability, targeting, and efficacy.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR02005K
Research progress of norcantharidin nanodrugs for tumor treatment
This review summarizes recent advances in norcantharidin (NCTD)-based nanomedicines for tumor therapy, focusing on four major research areas: prodrug modification, encapsulation and delivery, immunotherapy, and combination therapy.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01530H
Photocatalytic synthesis of hydrogen peroxide: recent advances, challenges, and future perspectives
General overview of the optimization strategies for high-efficiency photocatalytic H2O2 production.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR02034D
Structural modification strategies for ferritin nanoparticles and their applications in biomedicine: a narrative review
Engineered ferritin nanocages exploit biocompatibility and TfR1 targeting. Chemical/genetic/mineralization strategies enable therapeutics delivery, imaging, and vaccines (in trials). Advancing smart precision nanomedicine.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01369K
Nanomotor-mediated drug delivery with efficient blood–brain barrier crossing for active targeting and therapy of glioblastomas: a systematic review
Chemotactic nanomotors, bubble-driving nanomotors, photothermal nanomotors, and dual-powered nanomotors, provide superior cellular uptake, BBB crossing, and deep tumor penetration, thus specifically targeting and treating glioblastoma.
Nanoscale, 2025,17, 16592-16608
https://doi.org/10.1039/D5NR02445E
Research progress on functional solid polymer electrolytes for lithium batteries
Overview of polymer solid electrolytes based on different functionalities.
Nanoscale, 2025,17, 16560-16591
https://doi.org/10.1039/D5NR01513H
Leveraging Metal Sites in Doped Metal Halide Perovskites toward Enhanced Photocatalysis: Fundamentals and Applications
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR02472B
Silver Nanoparticles with Multimodal Biological Activities Integrated into Advanced Material Platforms for Chronic Wound Management
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR02066B

Nanoparticle-based biosensors for virus detection in food systems: from farm to fork
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01459J
Recent progress in outermost surface engineering for solar panels
This paper briefly outlines the basic concepts and current developments in anti-reflection, anti-smudge, and spectrum regulation technologies, discussing the challenges and trends related to the applications on the surface of solar cells.
Nanoscale, 2025,17, 16071-16099
https://doi.org/10.1039/D5NR00621J
Recent progress in polyaniline-based catalysts for electrochemical energy conversion
This review clearly summarizes recent synthesis and applications of polyaniline (PANI)-based composites in electrocatalysis field, enhancing understanding of PANI-based electrocatalysts and inspiring future electrocatalyst design.
Nanoscale, 2025,17, 16114-16152
https://doi.org/10.1039/D5NR00966A
Electrocatalytic nitrogen reduction: mechanisms, system-level optimization, and future perspectives
We summarize the current state of eNRR technology, mechanisms, and potential optimization strategies, providing inspiring guidance for the eNRR.
Nanoscale, 2025,17, 16100-16113
https://doi.org/10.1039/D5NR01582K
Interplay between the shape anisotropy and optical properties of Cu- and Ag-based ternary and quaternary chalcogenide nanocrystals
This review highlights the development of ternary and quaternary Cu- and Ag-based chalcogenide NCs with anisotropic shapes: synthesis methods, spectral properties, including chiroptical, energy level structure and potential applications.
Nanoscale, 2025,17, 16193-16212
https://doi.org/10.1039/D5NR01376C
Advances of nano-photofertilizers in plant research
The work summarized the light-responsive nanomaterials for plant research including their interactions with plants and recent advancements in their photon-mediated imaging, growth regulation, detection and antimicrobial applications. Images reproduced with permission; full details in paper.
Nanoscale, 2025,17, 16153-16192
https://doi.org/10.1039/D5NR00906E
Multi-scale assembly strategies driven by arene–perfluoroarene interaction: molecular design of functional materials
The arene–perfluoroarene force enables coassemblies with pronounced optical properties, which provide protocols for fabricating chiroptical materials.
Nanoscale, 2025,17, 16056-16070
https://doi.org/10.1039/D5NR01626F
Recent advances in 2D materials-based infrared photodetectors highlighting progress and future prospects
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01920F
Unlocking the Potential of Potassium-Ion Batteries: Anode Material Mechanisms, Challenges, and Future Directions
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR01667C
Optoelectronic MXene quantum dots: frontiers in sensor technology for next-generation diagnostics and environmental monitoring
MXene QDs are illustrated, showcasing their synthesis, properties, and emerging applications in next-generation diagnostics and environmental monitoring.
Nanoscale, 2025,17, 15554-15591
https://doi.org/10.1039/D5NR00854A
Advances in nanomaterial thin-film temperature sensors: materials and applications
This review provides a comparative overview of thin-film temperature sensors based on five major material groups, highlighting their mechanisms, strengths, limitations, and integration into wearable, e-skin, and robotic applications.
Nanoscale, 2025,17, 15592-15604
https://doi.org/10.1039/D5NR01099C

Advancing electrocatalytic CO2 reduction: key strategies for scaling up to industrial applications
This review explores recent advances in catalyst design, reactor configuration, system optimization, and mechanistic insights to drive CO2 electrolysis technology toward large-scale and commercial applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01624J
Bibliometric review on flexible pressure sensor design strategies
This review summarizes advancements in flexible pressure sensor design, including materials, devices, algorithm design, and systems, using bibliometric methods. The materials used in the system section are sourced from Vecteezy (Vecteezy.com).
Nanoscale, 2025,17, 14999-15028
https://doi.org/10.1039/D5NR00394F
Two-dimensional anisotropic semiconductors: from structure and properties to device applications
This review systematically summarizes the electronic band structures, optical properties and device applications of 2D anisotropic semiconductors.
Nanoscale, 2025,17, 15086-15109
https://doi.org/10.1039/D5NR01305D

Advancing extracellular vesicle production: improving physiological relevance and yield with 3D cell culture
3D cell cultures produce higher EV yields, with comparable or more physiologically relevant morphology, enriched cargo, and enhanced functionality. However, each model presents distinct strengths and limitations that must be carefully considered.
Nanoscale, 2025,17, 15110-15131
https://doi.org/10.1039/D5NR00707K
Engineering tough, energy-dissipating soft materials via sacrificial chemical bonds
This review outlines the chemical toolkit for energy-dissipating sacrificial bonds by surveying recent (post-2017) developments in tough, impact-resistant soft materials.
Nanoscale, 2025,17, 15029-15067
https://doi.org/10.1039/D5NR00018A
A review: metal and metal oxide nanoparticles for environmental applications
Environmental applications of metal and metal oxide nanoparticles primarily comprise contaminant adsorbents, catalysts, and sensors for hazardous substances, etc.
Nanoscale, 2025,17, 15068-15085
https://doi.org/10.1039/D5NR01973G
About this collection
In addition to high impact and high quality research across nanoscience & nanotechnology, Nanoscale publishes topical review articles. Reviews will be added to this webpage as soon as possible after publication.