Themed collection 2024 Emerging Investigators

Contributors to the 2024 Emerging Investigators collection
This profile article showcases the researchers who have contributed an article to the 2024 Emerging Investigators collection.
Chem. Soc. Rev., 2025, Advance Article
https://doi.org/10.1039/D5CS90030A
Implantable hydrogels as pioneering materials for next-generation brain–computer interfaces
Hydrogels are emerging as promising candidates for brain–computer interfaces. This review highlights the current advancements in implantable hydrogel electrodes for neural signal recording, neuromodulation, and brain disorder treatment.
Chem. Soc. Rev., 2025,54, 2832-2880
https://doi.org/10.1039/D4CS01074D

Coacervates as enzymatic microreactors
We review advances in coacervate-based microreactors, covering enzyme selection, recruitment strategies, microreactor compositions, and their impact on reaction kinetics.
Chem. Soc. Rev., 2025, Advance Article
https://doi.org/10.1039/D4CS01203H
Interfacial fluid manipulation with bioinspired strategies: special wettability and asymmetric structures
Bioinspired fluid manipulating interfaces possessing special wettability, an asymmetric structure, and a geometric gradient were systematically reviewed, including history, classification, mechanisms, fabrication and applications.
Chem. Soc. Rev., 2025,54, 1733-1784
https://doi.org/10.1039/D4CS01073F
Recent advances and design strategies for organic afterglow agents to enhance autofluorescence-free imaging performance
Organic afterglow luminescence can emit light long after the cessation of irradiation, enabling autofluorescence-free in vivo imaging with high signal-to-background ratios (SBRs).
Chem. Soc. Rev., 2025,54, 1429-1452
https://doi.org/10.1039/D4CS01060D
Diastereodivergence in catalytic asymmetric conjugate addition of carbon nucleophiles
This review explores various catalytic strategies for achieving diverse diastereomeric outcomes in asymmetric conjugate additions creating carbon–carbon bonds.
Chem. Soc. Rev., 2025,54, 715-741
https://doi.org/10.1039/D4CS00485J

Exploring porous structures without crystals: advancements with pair distribution function in metal- and covalent organic frameworks
This review highlights the importance of pair distribution function (PDF) analysis in revealing molecular interactions, structural transformations, and nucleation mechanisms in metal- and covalent organic frameworks (MOFs and COFs).
Chem. Soc. Rev., 2024,53, 11772-11803
https://doi.org/10.1039/D4CS00267A
Mechanism and stereoselectivity in metal and enzyme catalyzed carbene insertion into X–H and C(sp2)–H bonds
This review provides a mechanistic overview of asymmetric Fe, Cu, Pd, Rh, Au and heme-based enzymes catalyzed carbene insertion reactions to construct C–X (X = O, N, S, etc.) and C–C bonds, focusing on the stereochemical models.
Chem. Soc. Rev., 2024,53, 11004-11044
https://doi.org/10.1039/D4CS00742E
Light/X-ray/ultrasound activated delayed photon emission of organic molecular probes for optical imaging: mechanisms, design strategies, and biomedical applications
Versatile energy inputs, including light, X-ray and ultrasound, activate organic molecular probes to undergo different delay mechanisms, including charge separation, triplet exciton stabilization and chemical trap, for delayed photon emission.
Chem. Soc. Rev., 2024,53, 10970-11003
https://doi.org/10.1039/D4CS00599F
PEDOT-based stretchable optoelectronic materials and devices for bioelectronic interfaces
This review summarized the strategies and mechanisms for improving the conductivity, mechanical properties and stability of PEDOT:PSS, as well as the reliable micropatterning technologies and optoelectronic devices applied at bio-interfaces.
Chem. Soc. Rev., 2024,53, 10575-10603
https://doi.org/10.1039/D4CS00541D
Chemistry, applications, and future prospects of structured liquids
This review article centers around structured liquids and their underlying mechanisms. The focus is on the chemistry, applications, characterization, reconfigurability, and future prospects of this class of soft materials.
Chem. Soc. Rev., 2024,53, 9652-9717
https://doi.org/10.1039/D4CS00549J
Proteolysis-targeting drug delivery system (ProDDS): integrating targeted protein degradation concepts into formulation design
This review proposes the concept of proteolysis-targeting drug delivery system (ProDDS), surveys the recent research in various ProDDSs, summarizes their design principles, and provides an outlook on future opportunities.
Chem. Soc. Rev., 2024,53, 9582-9608
https://doi.org/10.1039/D4CS00411F
Bioelectronics for electrical stimulation: materials, devices and biomedical applications
Bioelectronics is a hot research topic, yet an important tool, as it facilitates the creation of advanced medical devices that interact with biological systems to effectively diagnose, monitor and treat a broad spectrum of health conditions.
Chem. Soc. Rev., 2024,53, 8632-8712
https://doi.org/10.1039/D4CS00413B
Ion transport mechanisms in covalent organic frameworks: implications for technology
This review explores designing highly ion-conductive COFs for advanced electrochemical devices, merging theory and practice.
Chem. Soc. Rev., 2024,53, 8182-8201
https://doi.org/10.1039/D4CS00409D
Advancing H2O2 electrosynthesis: enhancing electrochemical systems, unveiling emerging applications, and seizing opportunities
Recent achievements in H2O2 electrosynthesis are reviewed, including electrocatalyst design, electrode optimization, electrolyte engineering, reactor exploration, potential applications, and integrated systems.
Chem. Soc. Rev., 2024,53, 8137-8181
https://doi.org/10.1039/D4CS00412D
Atomic engineering of two-dimensional materials via liquid metals
The usage of liquid metal or alloy enables the fabrication of various 2D atomic crystals. This review fully examines the synthetic methods, condition-behavior relationship, and atomic engineering in this field, emphasizing a promising future.
Chem. Soc. Rev., 2024,53, 7158-7201
https://doi.org/10.1039/D4CS00295D
Catalysis under electric-/magnetic-/electromagnetic-field coupling
This review outlines recent advances in field-regulated catalysis and reveals the key role of dipole manipulation by electric/magnetic/electromagnetic fields.
Chem. Soc. Rev., 2025,54, 524-559
https://doi.org/10.1039/D4CS00869C

Unifying thermochemistry concepts in computational heterogeneous catalysis
Thermophysical properties of adsorbates and gas-phase species define the free energy landscape of heterogeneously catalyzed processes and are pivotal for an atomistic understanding of the catalyst performance.
Chem. Soc. Rev., 2025,54, 560-589
https://doi.org/10.1039/D4CS00768A
Intrinsic immunomodulatory hydrogels for chronic inflammation
This tutorial review presents the development of advanced immunomodulatory hydrogels strategically designed to address chronic inflammation through their intrinsic properties.
Chem. Soc. Rev., 2025,54, 33-61
https://doi.org/10.1039/D4CS00450G
Multidimensionally ordered mesoporous intermetallics: Frontier nanoarchitectonics for advanced catalysis
This perspective summarizes recent progress in rational design and synthesis of multidimensionally ordered mesoporous intermetallics, and propose new frontier nanoarchitectonics for designing high-performance functional nanocatalysts.
Chem. Soc. Rev., 2024,53, 11321-11333
https://doi.org/10.1039/D4CS00484A
From cyclotrons to chromatography and beyond: a guide to the production and purification of theranostic radiometals
This tutorial review explores the fundamentals and applications behind the production and purification of radiometals in the burgeoning field of radio-theranostics.
Chem. Soc. Rev., 2024,53, 10409-10449
https://doi.org/10.1039/D4CS00802B

Supramolecular and molecular capsules, cages and containers
Supramolecular and molecular capsules are a diverse class of host systems exhibiting a range of properties and characteristics with applications in sensing, separations, storage, transport, reactivity modulation and biomedicine.
Chem. Soc. Rev., 2024,53, 10380-10408
https://doi.org/10.1039/D4CS00761A
Organocatalytic enantioselective construction of Si-stereocenters: recent advances and perspectives
This Tutorial Review discusses the evolution and expectation of enantioselective construction of Si-stereocenters by asymmetric organocatalysis.
Chem. Soc. Rev., 2024,53, 8546-8562
https://doi.org/10.1039/D4CS00417E

Strongly-confined colloidal lead-halide perovskite quantum dots: from synthesis to applications
Reducing the dimensionality of lead-halide perovskite nanocrystals from 3D to 0D leads to fascinating properties. This tutorial review discusses the synthesis, optical properties and applications of such strongly-confined quantum dots.
Chem. Soc. Rev., 2024,53, 8095-8122
https://doi.org/10.1039/D4CS00077C

Recent advances in oxidative degradation of plastics
Oxidative degradation is a powerful method to degrade plastics into oligomers and small oxidized products.
Chem. Soc. Rev., 2024,53, 7309-7327
https://doi.org/10.1039/D4CS00407H
Recent advances in tunable solid-state emission based on α-cyanodiarylethenes: from molecular packing regulation to functional development
An overview of the design strategies and their applications of tunable molecular solid-state emission based on customized packing of α-cyanodiarylethenes (CAEs) by stimuli response as well as the utilization of co-assembly.
Chem. Soc. Rev., 2024,53, 6636-6653
https://doi.org/10.1039/D4CS00325J
About this collection
We are delighted to present the Chemical Society Reviews 2024 Emerging Investigators collection.
This collection showcases the high quality work of early career scientists who are internationally recognised for making outstanding contributions to their respective fields. New articles will be added to this collection as they are published.