Themed collection Food & Function Review Articles 2025


Is moderate beer consumption associated with poor dietary and biochemical parameters of nutritional status in adults? A systematic review of observational and interventional studies with meta-analysis
The impact of heavy alcohol consumption on health and nutritional status is well-documented, but the effects of moderate beer consumption remain less well understood.
Food Funct., 2025, Advance Article
https://doi.org/10.1039/D5FO01788B
Dietary microRNAs in Aging: Sources, Mechanisms, Translational Potential, and Future Directions
Food Funct., 2025, Accepted Manuscript
https://doi.org/10.1039/D5FO01825K
Probiotics enhance vitamin absorption in the intestine: influencing factors and potential mechanisms
Probiotics enhance vitamin absorption by modulating gut microbiota, regulating intestinal pH/metabolism, and influencing transporter proteins.
Food Funct., 2025,16, 5665-5678
https://doi.org/10.1039/D4FO04252B

Polysaccharides from echinoderms: unlocking health benefits and food applications – a review
Polysaccharides from echinoderms show diverse structures with unique functional properties. Their bioactivities including anti-inflammatory, antioxidant and anticoagulant effects, highlight their potential in health and functional food applications.
Food Funct., 2025,16, 5679-5704
https://doi.org/10.1039/D5FO02177D
Strawberry as a health promoter: an evidence-based review. Where are we 10 years later?
Strawberries are commonly consumed berries in the Mediterranean area.
Food Funct., 2025,16, 5705-5732
https://doi.org/10.1039/D5FO01888A
Molecular mechanisms of aberrant fatty acids metabolism in driving cardiovascular diseases: key regulatory targets and dietary interventions
Aberrant fatty acid metabolism promotes cardiovascular disease via oxidative stress, inflammation, and vascular dysfunction. Targeting key pathways and optimizing lipid intake offers promising strategies for prevention and treatment.
Food Funct., 2025, Advance Article
https://doi.org/10.1039/D5FO01237F

Effects of vegan diets and lifestyle on adult body composition: a narrative review
The health benefits of vegan diets are well documented, though achieving nutritional adequacy requires careful planning, as is the case with any well-designed diet.
Food Funct., 2025, Advance Article
https://doi.org/10.1039/D5FO01876E
The effects of Lacticaseibacillus rhamnosus GG supplementation on gastrointestinal and respiratory outcomes: a systematic review and meta-analysis of randomized controlled trials
Food Funct., 2025, Accepted Manuscript
https://doi.org/10.1039/D5FO01780G
Dietary strategies for appetite regulation: satiety and obesity management
Different nutrients and metabolites affect appetite signals and the feed desire.
Food Funct., 2025,16, 5202-5218
https://doi.org/10.1039/D5FO01349F

The potential effect of polyphenols in emerging pharmacological liver targets for glucose regulation and insulin resistance: a review
Polyphenols have gained attention for modulating hepatic pathways critical to glucose homeostasis in type 2 diabetes. This review examines their effects on key liver targets, highlighting research gaps and their relevance in diabetes management.
Food Funct., 2025,16, 5231-5277
https://doi.org/10.1039/D4FO06329E
Biomarkers of fried food intake: a systematic review of in vivo studies
In vivo studies disclose biomarkers of fried food intake, via MS-based metabolomics.
Food Funct., 2025,16, 5219-5230
https://doi.org/10.1039/D4FO05008H
1-Deoxynojirimycin: a comprehensive review of sources, biosynthesis pathways, strategies to enhance its production, and anti-diabetic activities
In this article, we provide a comprehensive review of the main sources and biosynthesis pathways of 1-dnj, strategies to increase its production, and the therapeutic effects and mechanisms of 1-dnj on diabetes mellitus (DM) and various diabetic complications.
Food Funct., 2025,16, 4673-4701
https://doi.org/10.1039/D4FO04954C
Gut microbe-derived pentadecanoic acid could represent a novel health-promoter via multiple pathways
Gut microbiota-derived PA, an odd-chain saturated fatty acid, can modulate several signaling pathways to hold great promise for the treatment of several diseases.
Food Funct., 2025,16, 4636-4653
https://doi.org/10.1039/D5FO01278C
Chlorogenic acid and intestinal health: mechanistic insights and therapeutic applications
Chlorogenic acid (CGA), a polyphenolic compound found in various plant species, has shown considerable potential in the treatment and management of several diseases due to its potent bioactive properties.
Food Funct., 2025,16, 4257-4277
https://doi.org/10.1039/D5FO00853K
The interaction between starch and phenolic acids: effects on starch physicochemical properties, digestibility and phenolic acids stability
Starch and phenolic acids, two common plant-based food components, can interact to form complexes during food processing, thus improving the functional properties of both starch and phenolic acids.
Food Funct., 2025,16, 4202-4225
https://doi.org/10.1039/D5FO00855G
Harnessing food-derived bioactive peptides for iron chelation: an alternative solution to iron deficiency anemia
The combination of bioactive peptides from various food sources and iron enhances their therapeutic effect on iron deficiency anemia.
Food Funct., 2025,16, 4226-4241
https://doi.org/10.1039/D4FO05823B
Therapeutic potential of fucoidan in atherosclerosis: a review
Fucoidan from brown seaweed shows lipid-lowering, antioxidant, anti-inflammatory, endothelial-protective and prebiotic activities. These effects address key atherosclerosis mechanisms, making it a promising therapeutic candidate.
Food Funct., 2025,16, 4242-4256
https://doi.org/10.1039/D4FO05388E
Extraction, purification, structural characterization and bioactivity of maize oligosaccharides: a review
Maize (Zea mays L.), as a globally significant food and economic crop, has attracted considerable attention from both the academic and industrial sectors due to its rich nutrient components and wide-ranging application value.
Food Funct., 2025,16, 3800-3832
https://doi.org/10.1039/D5FO00791G
Fruits native to South America: a narrative review of their biological properties and chemical profiles
This review offers useful information to guide further research on fruits native to South America, which is a largely unexplored frontier, for developing novel antioxidant, anti-inflammatory, and antimicrobial compounds.
Food Funct., 2025,16, 3774-3799
https://doi.org/10.1039/D5FO00549C
Maternal obesity and offspring metabolism: revisiting dietary interventions
Maternal obesity increases the risk of metabolic disorders in offspring.
Food Funct., 2025,16, 3751-3773
https://doi.org/10.1039/D4FO06233G
Mussels as sustainable marine resources for bioactive peptides for health and the food industry
The growing need for sustainable protein sources has led to increased interest in marine-based alternatives, particularly those with bioactive properties.
Food Funct., 2025,16, 3255-3272
https://doi.org/10.1039/D4FO05397D
Preventive effects against cognitive decline and obesity via the combination of dietary factors and exercise: can dietary factors replace or complement the beneficial effects of exercise?
Combination of dietary factor intake and exercise enhances the preventive effect against obesity and improves cognitive function.
Food Funct., 2025,16, 3243-3254
https://doi.org/10.1039/D4FO06349J
Effects of polyphenols on non-alcoholic fatty liver disease: a case study of resveratrol
Plant polyphenols show good potential for preventing chronic metabolic diseases, especially resveratrol, by reducing insulin resistance and fat synthesis linked to non-alcoholic fatty liver disease.
Food Funct., 2025,16, 2926-2946
https://doi.org/10.1039/D4FO04787G
Insights from traditional fermented legumes towards the innovation of modern plant-based meat analogues
The future generation of plant-based meat alternatives may be based on ancient fermented foods with limited additives and processing steps.
Food Funct., 2025,16, 2637-2655
https://doi.org/10.1039/D4FO02035A

Dietary therapy to halt the progression of diabetes to diabetic kidney disease
Dietary therapy shows promise for diabetic kidney disease but requires personalization and further research.
Food Funct., 2025,16, 2622-2636
https://doi.org/10.1039/D4FO06011C
Goat milk oligosaccharides: regulating infant immunity by intervention in the gut microbiota
The health status of the growing infant is closely related to the development of the gut microbiota during infancy, which is also a major stimulator of the immune system.
Food Funct., 2025,16, 2213-2229
https://doi.org/10.1039/D5FO00162E
The association between overall, healthy, and unhealthy plant-based diet indexes and risk of all-cause and cause-specific mortality: a systematic review and dose–response meta-analysis of prospective cohort studies
Our research underscores the necessity of assessing the quality of plant-based foods to determine their classification as either healthy or unhealthy. This evaluation is crucial, as it relates to the risk of all-cause and cause-specific mortality.
Food Funct., 2025,16, 2194-2212
https://doi.org/10.1039/D4FO04741A
The interaction between various food components and intestinal microbiota improves human health through the gut–X axis: independently or synergistically
Food contains various components that improve health by affecting the gut microbiota, primarily by modulating its abundance or altering its diversity.
Food Funct., 2025,16, 2172-2193
https://doi.org/10.1039/D4FO04430D
Recent advances in the effect of simulated gastrointestinal digestion and encapsulation on peptide bioactivity and stability
Bioactive peptides may experience changes in bioactivity during digestion, depending on their stability and the bioactivity of their digestion products. Encapsulation enhances their gastrointestinal stability.
Food Funct., 2025,16, 1634-1655
https://doi.org/10.1039/D4FO04447A
Dietary and nutritional interventions for human diseases: their modulatory effects on ferroptosis
Interventions targeting ferroptosis are summarized from the perspective of dietary patterns, food and nutrients.
Food Funct., 2025,16, 1186-1204
https://doi.org/10.1039/D4FO05606J
A review on the effects of flavan-3-ols, their metabolites, and their dietary sources on gut barrier integrity
Gut barrier integrity is of fundamental importance for human health. Effects of flavan-3-ols, their metabolites, and their dietary sources in maintaining its functionality was analysed in this review.
Food Funct., 2025,16, 815-830
https://doi.org/10.1039/D4FO04721D
Dietary polyphenols for tumor therapy: bioactivities, nano-therapeutic systems and delivery strategies
This review provides a comprehensive evaluation of the anti-tumor bioactivities and delivery strategies of dietary polyphenols, as well as their application in the development of nano-therapeutic systems for tumor.
Food Funct., 2025,16, 853-866
https://doi.org/10.1039/D4FO04715J
Evaluating the differential benefits of varying carbohydrate-restricted diets on lipid profiles and cardiovascular risks in dyslipidemia: a meta-analysis and systematic review
This meta-analysis assesses long-term effects of CRDs with varying carbohydrate levels (MLCDs vs. LCDs) on metabolic outcomes in dyslipidemic patients, identifying MLCDs intake as a promising strategy for reducing CVDs risk in this population.
Food Funct., 2025,16, 831-852
https://doi.org/10.1039/D4FO05125D
A review of the role of bioactive components in legumes in the prevention and treatment of cardiovascular diseases
Cardiovascular diseases (CVD) represent a primary global health challenge.
Food Funct., 2025,16, 797-814
https://doi.org/10.1039/D4FO04969A
The mechanism of action of indole-3-propionic acid on bone metabolism
IPA binds to AhR and PXR receptors, regulating bone metabolic disorders.
Food Funct., 2025,16, 406-421
https://doi.org/10.1039/D4FO03783A
Camel milk extracellular vesicles/exosomes: a fascinating frontier in isolation and therapeutic potential
Camel milk has a unique composition that sets it apart from other types of animal milk, which has captured the interest of medical and scientific communities.
Food Funct., 2025,16, 344-365
https://doi.org/10.1039/D4FO04331F
Targeting the gut–skin axis by food-derived active peptides ameliorates skin photoaging: a comprehensive review
During skin photoaging, some FDAPs can be absorbed by the gut, pass through the blood barrier, and act on the skin. Some FDAPs can regulate gut microbiota, indirectly mitigating the effects of photoaging.
Food Funct., 2025,16, 366-388
https://doi.org/10.1039/D4FO04202F
Effect of fermented soybean on metabolic outcomes, anthropometric indices, and body composition: a systematic review and meta-analysis of clinical trials
The aim of the current study was to systematically review and quantify the findings of randomized controlled trials (RCTs) assessing the effect of fermented soy products on anthropometric indices, body composition, and metabolic outcomes.
Food Funct., 2025,16, 389-405
https://doi.org/10.1039/D4FO02668C
Unveiling the neuroprotective impact of virgin olive oil ingestion via the microbiota–gut–brain axis
The gut–brain axis, a complex system of two-way communication between both organs, plays a key role in overall health.
Food Funct., 2025,16, 24-39
https://doi.org/10.1039/D4FO04560B
The neurotoxicity of acrylamide in ultra-processed foods: interventions of polysaccharides through the microbiota–gut–brain axis
Acrylamide contained in UPFs is neurotoxic and will do harm to human intestine and brain through the MGB axis. Polysaccharides are active substances, which can alleviate the neurotoxicity caused by acrylamide by improving the MGB axis.
Food Funct., 2025,16, 10-23
https://doi.org/10.1039/D4FO03002H
Particle size effect of defatted rice bran on the gel properties and flavor of silver carp surimi gels
This study evaluated the impact of defatted rice bran (DRB) particle sizes (103.67–6.04 μm) on the gel properties and flavor of silver carp surimi gels.
Food Funct., 2025,16, 3308-3324
https://doi.org/10.1039/D5FO00302D
About this collection
This themed collection features recent review articles published in Food & Function.