Themed collection Journal of Materials Chemistry B Recent Review Articles
![](https://www.rsc-cdn.org/pubs-core/2022.0.159/content/NewImages/Ajax-GA-Loader.gif)
Designing iron oxide & silver nanocomposites with phyto- and fungo chemicals for biomedicine: lessons learned
This work summarises our findings regarding multifunctional complex iron oxide and silver nanoparticles produced with the plants Z. officinale, H. perforatum and mushrooms A. muscaria, S. crispa.
J. Mater. Chem. B, 2025,13, 1500-1517
https://doi.org/10.1039/D4TB02284J
Unleashing the antibacterial potential of ZIFs and their derivatives: mechanistic insights
Exploring the mechanisms underlying the antibacterial activity of Zeolitic Imidazolate Frameworks (ZIFs) and their derivatives.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02682A
Beyond DAD: proposing a one-letter code for nucleobase-mediated molecular recognition
This perspective outlines some key considerations for formulating a unified shorthand to describe nucleobase-mediated molecular recognition across chemical, biological, and materials contexts and proposes a naming scheme consistent therewith.
J. Mater. Chem. B, 2025,13, 485-495
https://doi.org/10.1039/D4TB01999G
Comprehensive Insights into Electrochemical Nicotine Sensing Technologies
J. Mater. Chem. B, 2025, Accepted Manuscript
https://doi.org/10.1039/D4TB02753A
Bacterial Outer Membrane Vesicles in Tumor Prevention and Treatment: Advancements in the Research and Application
J. Mater. Chem. B, 2025, Accepted Manuscript
https://doi.org/10.1039/D4TB01899K
Mechanistic understanding of pH as a driving force in cancer therapeutics
The development of pH-directed nanoparticles for tumor targeting represents a significant advancement in cancer biology and therapeutic strategies.
J. Mater. Chem. B, 2025,13, 2640-2657
https://doi.org/10.1039/D4TB02083A
Versatile hydrogels prepared by microfluidics technology for bone tissue engineering applications
This review comprehensively discusses the progress and future applications of microfluidic hydrogel technology in bone regeneration, especially their advantages over traditionally prepared hydrogels in bone tissue engineering.
J. Mater. Chem. B, 2025,13, 2611-2639
https://doi.org/10.1039/D4TB02314E
Programmable short peptides for modulating stem cell fate in tissue engineering and regenerative medicine
The schematic representation of biomedical applications of short peptides in cancer therapy, regenerative medicine, and tissue engineering.
J. Mater. Chem. B, 2025,13, 2573-2591
https://doi.org/10.1039/D4TB02102A
Advances in adhesion of microneedles for bioengineering
Microneedles require robust adhesion to perform well in challenging environments. Advanced adhesion mechanisms enable specialized designs, ensuring comfort and effectiveness for diverse medical and therapeutic applications.
J. Mater. Chem. B, 2025,13, 2592-2610
https://doi.org/10.1039/D4TB02517B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.159/content/NewImages/open-access-icon-orange.png)
Metallic Nanomaterials in Parkinson's Disease: A Transformative Approach for Early Detection and Targeted Therapy
J. Mater. Chem. B, 2025, Accepted Manuscript
https://doi.org/10.1039/D4TB02428A
Application of silk fibroin-based composite films in biomedicine and biotechnology
This article provides a comprehensive examination of recent advancements in silk fibroin-based composite films, with a focus on their applications in bone regeneration, wound healing, and health monitoring.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02616K
Advancements in 3D Gel Culture Systems for Enhanced Angiogenesis in Bone Tissue Engineering
J. Mater. Chem. B, 2025, Accepted Manuscript
https://doi.org/10.1039/D4TB01139B
Exploring the multifaceted roles of metal–organic frameworks in ecosystem regulation
This review provides a comprehensive analysis on the applications of various MOFs in both microbial eradication and protection, emphasizing their potential as promising smart materials in the field of ecosystem regulation.
J. Mater. Chem. B, 2025,13, 2272-2294
https://doi.org/10.1039/D4TB01882F
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.159/content/NewImages/open-access-icon-orange.png)
Evolution of branched peptides as novel biomaterials
Branched peptide-based systems mimic dendritic structures to improve biomaterial performance for medical applications with slower degradation, greater stiffness, and self-assembly capabilities.
J. Mater. Chem. B, 2025,13, 2226-2241
https://doi.org/10.1039/D4TB01897D
Biodegradable semiconducting polymer nanoparticles for phototheranostics
This review summarizes recent advances in biodegradable semiconducting polymer nanoparticles for phototheranostics, such as tumor imaging, lymph node imaging, as well as phototherapy, photo-immunotherapy, and anti-infection therapy.
J. Mater. Chem. B, 2025,13, 2242-2253
https://doi.org/10.1039/D4TB02437K
Plant-derived exosome-like nanoparticles in tissue repair and regeneration
This article reviews the extraction and characterization of ELNs, discussing their structure-function relationship. It examines recent advances in ELNs for tissue regeneration and highlights challenges and future directions in tissue repair and regeneration.
J. Mater. Chem. B, 2025,13, 2254-2271
https://doi.org/10.1039/D4TB02394C
Precision therapeutics for inflammatory bowel disease: advancing ROS-responsive nanoparticles for targeted and multifunctional drug delivery
This review discusses ROS-responsive nanoparticles in IBD therapy, highlighting challenges, solutions, and the “layered programmable delivery” strategy for enhanced drug delivery and localized treatment.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02868F
Tailoring Nanovectors for Optimal Neoantigen Vaccine Efficacy
J. Mater. Chem. B, 2025, Accepted Manuscript
https://doi.org/10.1039/D4TB02547D
A promising mesoporous silica carrier material for the diagnosis and treatment of liver diseases: recent research advances
The therapeutic diagnosis of liver diseases has garnered significant interest within the medical community.
J. Mater. Chem. B, 2025,13, 1935-1960
https://doi.org/10.1039/D4TB01822B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.159/content/NewImages/open-access-icon-orange.png)
Collagen as a bio-ink for 3D printing: a critical review
The significance of three-dimensional (3D) bioprinting in the domain of regenerative medicine and tissue engineering is readily apparent.
J. Mater. Chem. B, 2025,13, 1890-1919
https://doi.org/10.1039/D4TB01060D
The application of aptamers in the repair of bone, nerve, and vascular tissues
Schematic diagram of the application of aptamers in the repair of bone, nerve, and vascular tissues.
J. Mater. Chem. B, 2025,13, 1872-1889
https://doi.org/10.1039/D4TB02180K
Drug delivery systems loaded with plant-derived natural products for dental caries prevention and treatment
Schematic diagram of drug delivery system for dental caries prevention and treatment.
J. Mater. Chem. B, 2025,13, 1920-1934
https://doi.org/10.1039/D4TB01924E
Next-generation biopolymer gels: innovations in drug delivery and theranostics
Theranostic use of smart gels for precise treatment and drug delivery.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02068E
Advances in cuproptosis harnessing copper-based nanomaterials for cancer therapy
This review discusses the recent developments in copper-based nanomaterials that utilize copper-induced cell death, categorized by materials systems, while highlighting the limitations of current cuproptosis related copper-based nanomaterials.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02746A
Xanthene-based NIR organic phototheranostics agents: design strategies and biomedical applications
Near-infrared fluorescence imaging is key in biological exploration. Short emission wavelengths of xanthene dyes limit their use. Structural modifications shift emissions to the NIR-I/II range, enhancing their biomedical applications.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02480J
Representative modeling of biocompatible MXene nanocomposites for next-generation biomedical technologies and healthcare
MXenes are a class of 2D transition metal carbides and nitrides (Mn+1XnT) that have attracted significant interest owing to their remarkable potential in various fields.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02478H
Nanomaterials and clinical SERS technology: broad applications in disease diagnosis
In this review, we highlight the advancements in clinical SERS diagnostics, the role of NMs-SERS and AI in enhancing SERS data analysis for precise diagnosis of chronic diseases and improving detection sensitivity, specificity, and reproducibility.
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02525C
Advances in nanozymes with peroxidase-like activity for biosensing and disease therapy applications
This review explores the different types of nanozymes with POD-like activity and discusses their activity regulation, particularly emphasizing their latest development trends and advances in biosensing and disease treatment.
J. Mater. Chem. B, 2025,13, 1599-1618
https://doi.org/10.1039/D4TB02315C
Exosomes of different cellular origins: prospects and challenges in the treatment of acute lung injury after burns
The unique properties of exosomes and their applications in ALI, particularly in the delivery of diverse drug molecules, are summarized. Additionally, the current challenges of the use of exosomes in the treatment of ALI are proposed.
J. Mater. Chem. B, 2025,13, 1531-1547
https://doi.org/10.1039/D4TB02351J
Emerging biosensing platforms based on metal–organic frameworks (MOFs) for detection of exosomes as diagnostic cancer biomarkers: case study for the role of the MOFs
The different roles of MOFs as carriers, labels, electrode modifiers, and fluorescence quenchers for the detection of exosomes are discussed.
J. Mater. Chem. B, 2025,13, 1586-1598
https://doi.org/10.1039/D4TB02465F
Advances in peptide/polymer antimicrobial assemblies
This review highlights the importance of peptide/polymer nano-antimicrobial systems in improving antimicrobial activity, stability, cytotoxicity, and bioavailability.
J. Mater. Chem. B, 2025,13, 1518-1530
https://doi.org/10.1039/D4TB02144D
Progress in the treatment of Alzheimer's disease based on nanosized traditional Chinese medicines
Advancements in nanotechnology and its applications in traditional Chinese medicine (TCM) can deliver active ingredients or components of TCM across the blood–brain barrier to the targeted brain area.
J. Mater. Chem. B, 2025,13, 1548-1572
https://doi.org/10.1039/D4TB02062F
Platelet-derived biomaterials for targeted drug delivery and tissue repair
Platelets are nucleic-free cells with a lifespan of 7–10 days in the bloodstream, playing a crucial role in various physiological processes such as hemostasis, thrombus formation, tumor development and metastasis, inflammation, and host defense.
J. Mater. Chem. B, 2025,13, 1573-1585
https://doi.org/10.1039/D4TB02477J
Ultrasmall metal nanoclusters as efficient luminescent probes for bioimaging
Ultrasmall metal nanoclusters (NCs, <2 nm) have emerged as a novel class of photoluminescent bioimaging probes. This review article examines how a metal NC-based probe is designed with desired functionalities for bioimaging applications.
J. Mater. Chem. B, 2025,13, 1180-1194
https://doi.org/10.1039/D4TB02207F
Polymeric nanoparticles in radiopharmaceutical delivery strategies
The potential applications of polymer nanoparticles (NPs) in the biomedical field have been the subject of extensive research.
J. Mater. Chem. B, 2025,13, 1270-1285
https://doi.org/10.1039/D4TB02076F
Design, fabrication, and application of bioengineering vascular networks based on microfluidic strategies
Technologies, biochemical factors, and applications involved in the fabrication of tissue engineered vascular networks based on microfluidic strategies.
J. Mater. Chem. B, 2025,13, 1252-1269
https://doi.org/10.1039/D4TB02047B
Development and application of hydrogels in pathogenic bacteria detection in foods
This review explores hydrogels as versatile materials for detecting foodborne pathogens, emphasizing their role in fast, sensitive, and specific bacteria detection through various sensing mechanisms.
J. Mater. Chem. B, 2025,13, 1229-1251
https://doi.org/10.1039/D4TB01341G
Progress in Chinese medicine monomers and their nanoformulations on myocardial ischemia/reperfusion injury
The aim of this review is to elucidate the pathomechanism of MIRI and present the latest developments in the use of TCM monomers and nanomaterials in combination with TCM monomers for the treatment of MIRI.
J. Mater. Chem. B, 2025,13, 1159-1179
https://doi.org/10.1039/D4TB02091J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.159/content/NewImages/open-access-icon-orange.png)
Non-Ti MXenes: new biocompatible and biodegradable candidates for biomedical applications
This review discusses the properties of non-Ti MXenes, such as biocompatibility, biodegradability, antibacterial activity, and neuroprotective effects, highlighting their potential in various biomedical applications in comparison with Ti MXenes.
J. Mater. Chem. B, 2025,13, 1212-1228
https://doi.org/10.1039/D4TB01904K
Crafting nature's wonders: nanoarchitectonics developments in bioinspired nanocellulose-based stimuli-responsive supramolecular matrices
This review provides a comprehensive overview of the recent advances in the development of stimuli-responsive nanocellulose-based drug delivery systems.
J. Mater. Chem. B, 2025,13, 1195-1211
https://doi.org/10.1039/D4TB01814A
Emerging bioengineering breakthroughs in precision diagnosis and therapy for endometriosis and adenomyosis
This review highlights the potential of bioengineering breakthroughs to transform the diagnosis and management of endometriosis and adenomyosis, emphasizing their role in advancing precision medicine and improving women's health.
J. Mater. Chem. B, 2025,13, 742-762
https://doi.org/10.1039/D4TB01755B
From experimental studies to computational approaches: recent trends in designing novel therapeutics for amyloidogenesis
This review highlights the integration of various experimental and computational methods to control amyloid aggregation process. We believe that this article will help researchers develop novel therapeutic methods that influence protein aggregation.
J. Mater. Chem. B, 2025,13, 858-881
https://doi.org/10.1039/D4TB01890G
Recent progress towards the development of fluorescent probes for the detection of disease-related enzymes
This review highlights the current advancements in the development of fluorescent probes for the selective detection of disease-relevant enzymes, focusing on their biocompatibility in in vivo models.
J. Mater. Chem. B, 2025,13, 763-801
https://doi.org/10.1039/D4TB01960A
Nebulized inhalation drug delivery: clinical applications and advancements in research
Nebulized inhalation is a non-invasive drug delivery method with fast onset, low dosage, and fewer side effects. This review covers its principles, devices, clinical applications, and future trends in respiratory and systemic diseases.
J. Mater. Chem. B, 2025,13, 821-843
https://doi.org/10.1039/D4TB01938E
Leveraging nanomaterials for ultrasensitive biosensors in early cancer detection: a review
Recent advances in nanotechnology revolutionize cancer diagnostics, better than PET-scans and biopsies. Ultrasensitive nanobiosensors spot trace biomarkers effectively, allowing early, precise detection and better outcomes, altering cancer care globally.
J. Mater. Chem. B, 2025,13, 802-820
https://doi.org/10.1039/D4TB02107J
Advancements in phasor-based FLIM: multi-component analysis and lifetime probes in biological imaging
This review focuses on lifetime probes in phasor-based FLIM and multi-component analysis in complex environments. Using three probes (a, b, c) with distinct lifetimes, it visualizes clusters in the phasor plot, enabling imaging of specific regions.
J. Mater. Chem. B, 2025,13, 472-484
https://doi.org/10.1039/D4TB01669F
Gold nanostars and nanourchins for enhanced photothermal therapy, bioimaging, and theranostics
Gold nanostars and nanourchins enhance photothermal therapy (PTT), an emerging tumor treatment that uses hyperthermia generated by photo-absorbing materials to eradicate cancer cells, while also enabling bioimaging and theranostic applications.
J. Mater. Chem. B, 2025,13, 399-428
https://doi.org/10.1039/D4TB01420K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.159/content/NewImages/open-access-icon-orange.png)
Recent advances in polymer-based thin-film electrodes for ECoG applications
This review evaluated electrocorticography (ECoG) electrode performance based on key properties and improvements from polymers, categorizing them as sensitive or structural, while discussing preparation methods, challenges, and future perspectives.
J. Mater. Chem. B, 2025,13, 454-471
https://doi.org/10.1039/D4TB02090A
Eco-friendly self-cleaning coatings: fundamentals, fabrication, applications, and sustainability
Eco-friendly self-cleaning coatings have garnered significant attention due to their potential to address environmental concerns while offering remarkable properties.
J. Mater. Chem. B, 2025,13, 429-453
https://doi.org/10.1039/D4TB01392A
Research progress of nitroxide radical-based MRI contrast agents: from structure design to application
Nitroxide radicals-based agnetic resonance imaging remains a cornerstone of diagnostic imaging, offering unparalleled insights into anatomical structures and pathological conditions.
J. Mater. Chem. B, 2025,13, 372-398
https://doi.org/10.1039/D4TB02272F
Experimental and computational techniques to investigate the protein resistance of zwitterionic polymers
Zwitterionic polymers exhibit exceptional protein resistance due to their hydration layer. Both experimental and computational techniques offer insights into the hydration effect and underlying mechanisms.
J. Mater. Chem. B, 2025,13, 103-116
https://doi.org/10.1039/D4TB01782J
Nanoparticles based image-guided thermal therapy and temperature feedback
This review explores nanoparticles in image-guided thermal therapy, highlighting their targeted treatment potential, temperature feedback, nanomaterial architectures, and applications in hyperthermia and precision medicine.
J. Mater. Chem. B, 2025,13, 54-102
https://doi.org/10.1039/D4TB01416B
Unravelling molecular mechanobiology using DNA-based fluorogenic tension sensors
Tiny piconewton level forces play a big role in the biological system.
J. Mater. Chem. B, 2025,13, 37-53
https://doi.org/10.1039/D4TB01858C
Biomaterials enhancing localized cancer therapy activated anti-tumor immunity: a review
This article reviews the application of biomaterials in combination with immunotherapy to enhance the localized treatment of tumors, along with the current challenges and future development directions in this field.
J. Mater. Chem. B, 2025,13, 117-136
https://doi.org/10.1039/D4TB01995D
Recent advances of versatile fluorophores for multifunctional biomedical imaging in the NIR-II region
This review first outlines the advantages of fluorescence imaging in the NIR-II region, followed by a comprehensive overview of recent advancements in NIR-II fluorophores and their versatile applications in biomedical imaging.
J. Mater. Chem. B, 2025,13, 15-36
https://doi.org/10.1039/D4TB01957A
Temperature-responsive properties of pH-sensitive poly(methacrylic acid)-grafted brush coatings with controlled wettability for cell culture
The underexplored temperature-responsive properties of PMAA were determined for grafted PMAA brushes, with distinct properties when polymerized (via SI-ATRP) from NaMAA (more hydrophilic and antifouling) and MAA (more hydrophobic and biocompatible).
J. Mater. Chem. B, 2025, Advance Article
https://doi.org/10.1039/D4TB02217C
About this collection
This collection contains recent Review-type articles published by Journal of Materials Chemistry B, the home for high impact applications, properties and synthesis of exciting new materials for biology and medicine.
New articles will be added to this collection as soon as possible after publication.