Themed collection 2025 Journal of Materials Chemistry B Chinese New Year

Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global health hazard.

This review summarizes fabrication strategies and manifold applications of electrospun organic/inorganic hybrid nanofibers in promoting the wound healing process.

VPNS/AuNR has a synergistic antimicrobial mechanism against bacteria through PDT and PTT for the treatment of wound infection.

A mitochondrial targeting copper dithiocarbamate induces intense immunogenic cuproptosis in cancer cells and macrophage M1 polarization. This emphasizes the potential of mitochondrial targeting cuproptosis inducers in cancer immunotherapy.

A microwave-thermal-sensitive ZIF-8@HA nanoplatform combined with conformal array antennas enhances MW thermal conversion efficiency, reduces tumor ablation time, and minimizes thermal damage to healthy tissues during treatment.

γ-Glutamyl transpeptidase (GGT) regulates glutathione (GSH), essential for cell functions and linked to cancer.

High-strength fibrous sensor can collect resistance signals from injured Achilles tendon and convert them into bearing stress with ideal accuracy, which would favor the assessment of tissue healing and pave the way for personalized treatment.

The waste collagen fiber reinforced conductive organic hydrogel sensor (BPGC-Gly) is environmentally adaptable and multifunctional for multi-modal health monitoring via temperature, humidity, strain, pressure and bioelectrical signal acquisition.

The 3D printed hydrogel scaffold loaded with Rg3 shows the best healing results with few remaining defects.

Schematic diagram of the preparation of the enzyme-responsive nanoplatform HA-CP@Fe₃O₄ and its application in the study of antibacterial infection in vivo.

An X-ray responsive RCNprotac with enhanced tumor accumulation for BRD4 proteolysis and enhanced radiosensitization is reported.

Traditional hydrogels are usually weak and brittle, which limit their application in articular cartilage replacement because cartilage is generally strong, tough, and elastic in nature.

Conductive hydrogel sensors have attracted attention for use in human motion monitoring detection, but integrating excellent biocompatibility, mechanical, self-adhesive, and self-healing properties, and high sensitivity into a hydrogel remains a challenge.

The MTX@HMSN/CS-loaded MN patch exhibited enhanced and sustained anti-inflammatory effects against psoriasis with a continuous release of MTX.

Designing wound dressings necessitates the crucial considerations of maintaining a moist environment and implementing effective bacterial control.

A 3D printed scaffold for photo-activated bacterial eradication and bone regeneration in treating infected mandibular defects.

Endogenous O₂ can be continuously generated by the catalysis of Ce in the lattice of CeO₂ to enhance ¹O₂ production via a type II PDT (energy transfer), and many other ROS (such as O₂⁻ and ·OH) can be produced via a type I PDT (electron transfer).

The constructed ZnS–Ti₃C₂/PLLA scaffolds were able to release H₂S gas to disrupt biofilm and further remove bacteria through photothermal. In addition, the Zn²⁺ released from the composite scaffolds could promote osteogenic differentiation of BMSCs.

An endoplasmic reticulum-targetable ratiometric probe for imaging the fluctuation of HOBr during ER stress was successfully developed.

An anti-freezing nanocomposite hydrogel with self-healing properties and conductivity was designed by introducing CNCs and PA. A flexible sensor based on the hydrogel has satisfactory sensitivity, stability, and durability at −15 °C.